Store Locator
Track Order
Close X

New Customer ? Start Here.

MAKE more HAPPEN
MAKE more HAPPEN
 

New day. New Daily Deals. Get them before they are gone!

WEEKLY AD
Please Wait

NARROW BY:

In Store Availability

Deals

Chemical Cleaner Type

Disinfecting

Natural

Environmental

Rating

Brand

Price

to

Need help?

Live Chat Call Customer Support 1 (800) STAPLES

Cleaning Chemicals

Tackle any mess with these cleaning chemicals, which are formulated to eliminate dirt and germs. For both large and small facilities, these cleaners will help you get through any task quickly. Select the perfect cleaner for any job from trusted brands like Arm & Hammer, Clorox, and Lysol.

Powerful Formulas
These cleaning chemicals are designed with powerful formulas that cut through grease, dirt, and debris. Many brands also contain disinfectants, so you can make any space safer for employees or family members to use. For windows or mirrors, select a glass cleaner that wipes away without leaving streaks or residue. Or, opt for a maximum strength cleaning fluid for high-traffic surfaces such as floors and toilets.

Flexible Use
Choose a surface-specific formula to protect the integrity of your wood or glass furniture. Or, if you want a versatile cleaner for your home or office, look for an all-purpose option that offers powerful cleaning on all types of surfaces. For maximum performance, opt for products that deodorize while they clean. Streamline the process with useful cleaning tools.

Easy Application
Don't worry about rustling up a bucket and cloths — many of these cleaning chemicals are designed for quick, easy application. Use disinfecting wipes to clean up any small mess and dispose of them in the trash when you're finished. Choose a convenient spray bottle to provide excellent coverage and keep your hands clean. For tough bathroom messes, opt for bottles with a spout to enable fast application and excellent directional control.

Large Supply
Stock your office supply cabinet with industrial-sized cleaning products to extend the time between refills. Or, choose multipacks for easy distribution in different rooms throughout your facility.

READ MORE +

Please Wait
error iconSorry, but an error has been made.
25 - 48 of 1008 items
  • Save an extra in the next 20 minutes. See details
    Lysol Deodorizing Cleaner, Lemon Scent, 1 gal.
    Item 568527
    Model 76334/76185

    Lysol® Deodorizing Cleaner, Lemon Scent, 1 gal.

    Customer Rating
    Lysol® Deodorizing Cleaner, Lemon Scent, 1 gal.
    4.5stars
    (5  reviews)
    • Lemon scent, 1 gal. refill
    • Used for a variety of needs to clean, disinfect and deodorize
    • Concentrated formula makes 64 gal. of cleaner
    USD
    Price:
    $16.92
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details

    Formula 409® Cleaner, Degreaser, Disinfectant

    Customer Rating
    Formula 409® Cleaner, Degreaser, Disinfectant
    5.0stars
    (12  reviews)
    • 32 oz. spray bottle or 1 gal. refill available
    • Cleans counters, tabletops, painted woodwork, stainless steel, plastic and tile
    • For use on the toughest stains and messes
    USD
    Price:
    As low as
    $3.49
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Toilet Bowl Brush & Caddy
    Item 186890
    Model 333-90

    Toilet Bowl Brush & Caddy

    Customer Rating
    Toilet Bowl Brush & Caddy
    4.0stars
    (3  reviews)
    USD
    Price:
    $8.79
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Fabuloso All-Purpose Cleaner, Lavender, 1 gal, 4/Case
    Item 637721
    Model CPM04307CT

    Fabuloso All-Purpose Cleaner, Lavender, 1 gal, 4/Case

    Customer Rating
    Fabuloso All-Purpose Cleaner, Lavender, 1 gal, 4/Case
    0.0stars
    (0  reviews)
    • Lavender scent, 1 gal bottle
    • Cleans while leaving a long-lasting scent
    • No rinsing needed
    USD
    Price:
    $52.49
    4/Case
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Clorox Automatic Toilet Bowl Cleaner, 3.5 oz., 2 Tablets/Pack
    Item 240959
    Model CLO30024

    Clorox® Automatic Toilet Bowl Cleaner, 3.5 oz., 2 Tablets/Pack

    Customer Rating
    Clorox® Automatic Toilet Bowl Cleaner, 3.5 oz., 2 Tablets/Pack
    4.0stars
    (3  reviews)
    • Rain clean scent, 2 tablets with bleach per pack
    • Kills 99.9% of common illness-causing germs in toilet bowl water with every flush
    • Helps prevent hard water, mineral and lime-scale stains
    USD
    Price:
    $7.69
    2/Pack
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Murphy Oil Soap® Household Cleaner Concentrate, 1 gal.
    Item 507529
    Model CPM01103

    Murphy Oil Soap® Household Cleaner Concentrate, 1 gal.

    Customer Rating
    Murphy Oil Soap® Household Cleaner Concentrate, 1 gal.
    5.0stars
    (7  reviews)
    • Unscented, 1 gal. concentrate
    • Makes 64 gal. of ready-to-use solution
    • Cleans wood, laminated surfaces, no-wax floors,plastic, ceramic tile and more
    USD
    Price:
    $23.59
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Mr. Clean Multi-Surface Antibacterial All-Purpose Cleaner, 24 oz.
    Item 957227
    Model PGC 82707

    Mr. Clean® Multi-Surface Antibacterial All-Purpose Cleaner, 24 oz.

    Customer Rating
    Mr. Clean® Multi-Surface Antibacterial All-Purpose Cleaner, 24 oz.
    5.0stars
    (6  reviews)
    • Summer citrus scent, 24 oz. bottle
    • Versatile 3-in-1 cleaner for any hard, washable surface
    • Formula leaves no dulling streaks
    USD
    Price:
    $4.99
    Each
    Save an extra in the next 20 minutes. See details
    Add to Cart
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Pledge Multi-Surface Clean & Dust Wipes, 25 Wipes/Pack
    Item 638779
    Model CB214629/21462

    Pledge® Multi-Surface Clean & Dust Wipes, 25 Wipes/Pack

    Customer Rating
    Pledge® Multi-Surface Clean & Dust Wipes, 25 Wipes/Pack
    5.0stars
    (21  reviews)
    USD
    Price:
    $7.99
    25 Wipes/Pack
    Save an extra in the next 20 minutes. See details
    Add to Cart
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Seventh Generation® Natural Dish Liquid Soap, Free & Clear, 25oz.
    Item 700937
    Model SEV 22733

    Seventh Generation® Natural Dish Liquid Soap, Free & Clear, 25oz.

    Customer Rating
    Seventh Generation® Natural Dish Liquid Soap, Free & Clear, 25oz.
    4.5stars
    (13  reviews)
    • Free & Clear scent, 25 oz. bottle
    • Non-toxic, biodegradable and hypo-allergenic
    • Free of chlorine, phosphates, and petroleum-based ingredients
    USD
    Price:
    $3.99
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Windex Cleaner Wipes, 28 Wipes/Pack
    Item 322841
    Model CB702325

    Windex® Cleaner Wipes, 28 Wipes/Pack

    Customer Rating
    Windex® Cleaner Wipes, 28 Wipes/Pack
    3.5stars
    (5  reviews)
    • 28 wipes per pack
    • Industrial-strength multipurpose cleaner is perfect for windows, mirrors and more
    • Cleans with Ammonia-D® for a streak-free shine
    USD
    Price:
    $6.59
    28 Wipes/Pack
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Scrubbing Bubbles®,  25 oz.
    Item 848243
    Model DRA94308EA

    Scrubbing Bubbles®, 25 oz.

    Customer Rating
    Scrubbing Bubbles®, 25 oz.
    4.0stars
    (6  reviews)
    • 25 oz.
    • Attacks scum and dirt and kills germs, mold and mildew
    • EPA registered, cleaner that disinfects and deodorizes
    USD
    Price:
    $4.99
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    LYSOL Power & Free Bathroom Cleaner, Cool Spring Breeze Scent, 22 oz.
    Item 957752
    Model REC85668

    LYSOL® Power & Free™ Bathroom Cleaner, Cool Spring Breeze Scent, 22 oz.

    Customer Rating
    LYSOL® Power & Free™ Bathroom Cleaner, Cool Spring Breeze Scent, 22 oz.
    4.0stars
    (38  reviews)
    • Cool spring breeze scent, 22 oz. spray bottle
    • Bleach free
    • Kills 99.9% of viruses & bacteria
    USD
    Price:
    $6.89
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Lysol Professional Antibacterial Kitchen Cleaner Spray, 32 oz.
    Item 518729
    Model 74411

    Lysol® Professional Antibacterial Kitchen Cleaner Spray, 32 oz.

    Customer Rating
    Lysol® Professional Antibacterial Kitchen Cleaner Spray, 32 oz.
    5.0stars
    (5  reviews)
    • Citrus scent, 32 oz. spray bottle
    • Removes tough food stains and greasy dirt as well as mildew stains and soap scum
    • Kills germs such as: Staphylococcus aureus, Salmonella choleraesuis, Mold and mildew, E-Coli, HIV-1 (AIDS Virus), and Herpes Simplex Virus Types 1 and 2.
    USD
    Price:
    $7.49
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details

    Clorox® Green Works™ Natural Cleaners

    Customer Rating
    Clorox® Green Works™ Natural Cleaners
    4.5stars
    (33  reviews)
    • Original scent, 64 oz. All-Purpos Refill, 32 oz. All-Purpose or 32 oz. Glass & Surface cleaner available
    • Works on glass, mirrors, appliances, stainless steel and sealed granite
    • Made of 99% natural ingredients that are non-toxic and biodegradable
    USD
    Price:
    As low as
    $4.29
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details

    Soft Scrub® Commercial Cleansers

    Customer Rating
    Soft Scrub® Commercial Cleansers
    5.0stars
    (11  reviews)
    • 25.4 oz. or 36 oz. bottles available
    • Ideal for sinks, counter tops, toilets, and ceramic tile
    • Removes dirt and soap scum with no harsh scratching
    USD
    Price:
    As low as
    $5.59
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Clorox® Anywhere Hard Surface Sanitizing Spray, 32 oz.
    Item 815926
    Model CXS01698

    Clorox® Anywhere® Hard Surface™ Sanitizing Spray, 32 oz.

    Customer Rating
    Clorox® Anywhere® Hard Surface™ Sanitizing Spray, 32 oz.
    5.0stars
    (1  reviews)
    • 32 oz. spray bottle
    • Convenient sanitizing for food contact surfaces
    • Kills 99.9% of bacteria that causes foodborne illness
    USD
    Price:
    $7.99
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Lysol® All-Purpose Cleaner, LEMON BREEZE, 32 oz.
    Item 662280
    Model RAC75352

    Lysol® All-Purpose Cleaner, LEMON BREEZE®, 32 oz.

    Customer Rating
    Lysol® All-Purpose Cleaner, LEMON BREEZE®, 32 oz.
    5.0stars
    (4  reviews)
    • LEMON BREEZE® scent, 32 oz. spray bottle
    • For use in kitchens and washrooms
    • Kills 99.9% of bacteria in 30 seconds on hard, nonporous surfaces
    USD
    Price:
    $4.79
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Nice Pak ® Sani-Wipe ® Cloth Surface Sanitizing Wipe, 100 Wipes/Tub
    Item 666202
    Model Q94384

    Nice Pak ® Sani-Wipe ® Cloth Surface Sanitizing Wipe, 100 Wipes/Tub

    Customer Rating
    Nice Pak ® Sani-Wipe ® Cloth Surface Sanitizing Wipe, 100 Wipes/Tub
    0.0stars
    (0  reviews)
    • Premoistened wipes for retail food establishments and noncommercial food service providers improve health and safety compliance
    • Kills 99.999% of staph, E. coli and shigella boydii on hard nonporous food contact surfaces in 60 seconds
    • Includes six canisters of 100 wipes
    USD
    Price:
    $54.99
    100 Wipes/Tub
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details

    Sani-Cloth Disinfecting Wipes Distributed by Staples ®

    Customer Rating
    Sani-Cloth Disinfecting Wipes Distributed by Staples ®
    4.0stars
    (15  reviews)
    • Available in Fresh Air or Lemon scent, 75 swipes per canister
    • Kills 99.9% of bacteria including E.Coli, Salmonella, Staph, Strep and other common household bacteria in 15 seconds on non-porous surfaces
    • Kills common cold & flu viruses
    USD
    Price:
    As low as
    $4.79
    75 Wipes/Tub
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details

    Lysol® DUAL ACTION™ Disinfecting Wipes

    Customer Rating
    Lysol® DUAL ACTION™ Disinfecting Wipes
    4.5stars
    (60  reviews)
    • Available in 75 wipes per tub
    • Citrus scent
    • Use one side for everyday touch-ups and the other to scrub through tough messes
    USD
    Price:
    As low as
    $6.29
    75 Wipes/Tub
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    LYSOL Power & Free Toilet Bowl Cleaner, Cool Spring Breeze Scent, 24 oz.
    Item 957751
    Model REC85020

    LYSOL® Power & Free™ Toilet Bowl Cleaner, Cool Spring Breeze Scent, 24 oz.

    Customer Rating
    LYSOL® Power & Free™ Toilet Bowl Cleaner, Cool Spring Breeze Scent, 24 oz.
    4.0stars
    (36  reviews)
    • Cool spring breeze scent, 24 oz. squirt bottle
    • Dissolves lime scale and rust stains
    • No harsh chemical residue
    USD
    Price:
    $4.09
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Plastic Spray Bottles, 24 oz., 3/Pack
    Item 721707
    Model 721707-90

    Plastic Spray Bottles, 24 oz., 3/Pack

    Customer Rating
    Plastic Spray Bottles, 24 oz., 3/Pack
    4.0stars
    (6  reviews)
    USD
    Price:
    $9.79
    3/Pack
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Professional Lysol® Disinfectant Toilet Bowl Cleaner, Wintergreen, 32 oz. Bottle
    Item 870432
    Model REC74278

    Professional Lysol® Disinfectant Toilet Bowl Cleaner, Wintergreen, 32 oz. Bottle

    Customer Rating
    Professional Lysol® Disinfectant Toilet Bowl Cleaner, Wintergreen, 32 oz. Bottle
    0.0stars
    (0  reviews)
    • Wintergreen scent, 32 oz. bottle
    • Cleans, disinfects and deodorizes toilets and urinals
    • Liquid formula clings for longer contact
    USD
    Price:
    $41.49
    12/Pack
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
  • Save an extra in the next 20 minutes. See details
    Drano® Max Gel Drain Cleaner;  80 oz.
    Item 322845
    Model CB401099

    Drano® Max Gel Drain Cleaner; 80 oz.

    Customer Rating
    Drano® Max Gel Drain Cleaner; 80 oz.
    4.5stars
    (2  reviews)
    • Commercial size, 80 oz.
    • Will not harm pipes when used overnight
    • Safe for pipes, septic systems and garbage disposals
    USD
    Price:
    $13.79
    Each
    Save an extra in the next 20 minutes. See details
    Out of Stock Online
25 - 48 of 1008 items
Compare
We are sorry, we have had technical difficulties, please try again
Deals! Get them now
SUBMIT
Join us on: