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Tissues are the unsung hero of every office, home and classroom. When looking for quality cold and flu supplies, facial tissue minimizes discomfort and sniffling.

Choose the Right Tissue Thickness and Size
Brands produce tissue in a variety of dimensions and thicknesses, accommodating both occasional snifflers and heavy-duty nose blowers. The majority of tissue products have nearly square dimensions of about 8 by 8 inches, but some are smaller. Those who go through many tissues may get more value out of smaller options and can choose designs that are about half as wide. Smaller tissues save space and minimize paper waste. Tissue thickness is generally measured in plies. The single-ply tissue is made with one layer of paper. Single-ply options are considerably thinner than other designs, and they tend to maximize value for those who use substantial amounts of tissue. Two-ply and 3-ply tissues have additional layers, so they offer enhanced durability and strength.

Extra-Soft Tissues Cushion Sensitive Noses Frequent tissue use can irritate the skin, particularly during a severe cold or persistent allergies. Ultra-soft tissue options are ideal for these situations. They are gentle on the skin, minimizing the risk of redness and dryness. Extra-soft tissues often have extra plies for a thicker texture. Small air pockets inside each tissue provide further protection for delicate skin. Lotion-treated tissue products serve two purposes: They prevent skin friction and provide moisture in dry environments.

Battle Germs with Enhanced Tissue Products
Cold and flu season causes even the healthiest people to keep a box of facial tissue on hand at all times. When illness is the trigger for tissue use, consider specialized products that are designed to ease symptoms and help users heal more quickly. Antiviral tissue products often contain a middle layer that is activated by moisture. This layer kills up to 99.9 percent of cold and flu viruses. This type of tissue can prevent the spread of illness, especially in an office or classroom. Another popular option is a box of cooling tissues. These wipes contain lotion and cooling moisturizers that are released on contact, relieving nose redness and soreness.

Various Package Sizes Fit Home and Business Needs
Having facial tissue readily available is an important part of hygiene. That's why brands offer these products in a variety of package sizes. Individual tissue packs are small enough to fit in pockets, purses and briefcases. Boxes for the home and office come in rectangular and square designs to suit a variety of surfaces. Refill packs are ideal for tissue boxes that are part of a room's decor, and bulk ordering options make it easy to keep face tissues available in any number of rooms.

Eco-Friendly Tissues Help Users go Green
The disposable nature of facial tissues is what makes them hygienic, and with environmentally friendly options, users can shrink their carbon footprint. Several brands create Forest Stewardship Council certified tissues. Sustainable brands often use recycled fiber and avoid chlorine bleach. Whether you want extra-soft or antiviral, you'll find the ideal tissue variety for every home, business and school user at Staples.
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Kleenex® Boutique Face Tissue, 2-Ply, 95 Sheets/Box, 6 Boxes/Pack (21271)
Item: 826830 / Model : 21271
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  • 95/Box, 6 Boxes/Case, 570 Sheets/Case
  • Each white Kleenex face tissue is 2-Ply, 8.4 x 8.2"
  • White, Unscented
9.89 $9.89 12.29 $12.29
6/Pack
Get it by Thu, Oct 25
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Price: $12.29
Instant Savings: -$2.40
$9.89*
6/Pack
*Price after savings
Kleenex® Flat Box Facial Tissue, 2-Ply, 36/Case
Item: 808298 / Model : 21400CT
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  • 2-ply, white tissue
  • 100 tissues/box, 36 boxes/case
  • Soft, strong and absorbent
55.99 $55.99
36/Carton
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Kleenex® Boutique™ Cube Box Facial Tissues, 2-Ply, White, 95/Box, 36 Boxes/Case (21271)
Item: 915714 / Model : 21270
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  • 95 Tissues/Box, 36 Cube Boxes/Case
  • 8.2" x 8.4" tissues
  • Single-fold sheets
75.99 $75.99
36/Carton
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Kleenex® 2-Ply Facial Tissue, Flat Box, 160 Sheets/Box, 3 Boxes/Pack
Item: 56014 / Model : 37392
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  • 160 tissues per box
  • 3 boxes per pack
  • White; 2 ply
5.99 $5.99
3/Pack
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Puffs Ultra Soft Facial Tissue Cube, 56 Sheets per Cube, 24/Carton (35038CT)
Item: 24309368 / Model : 35038CT
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  • Soft, Strong and Fragrance Free tissues that contain no lotion
  • Soft and 2X stronger when wet vs leading national regular brand
  • Dermatologist tested to be gentle on skin
63.99 $63.99 64.99 $64.99
24/Carton
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Price: $64.99
Instant Savings: -$1.00
$63.99*
24/Carton
*Price after savings
Kleenex® Facial Tissue, 2-Ply, 12/Case
Item: 470745 / Model : 03076
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  • White, 2-ply tissues
  • 125 tissues/box, 12 boxes/case
  • Soft, yet strong
20.49 $20.49
12/Carton
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Staples Choice
Staples Facial Tissues Flat Box, 2-Ply, 160 Sheets/Box, 4 Boxes/Pack
Staples Facial Tissues Flat Box, 2-Ply, 160 Sheets/Box, 4 Boxes/Pack
Item: 24322419 / Model : 53224
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  • 2-Ply Facial Tissue
  • Strong and Absorbent
  • 4 flat boxes/pack
4.49 $4.49
4/Pack
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Puffs Cube Ultra Soft 2-Ply Facial Tissues, 56/Box
Item: 2675854 / Model : 35295
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  • Facial Tissue
  • Puffs Ultra Soft and Strong is our most comforting lotionless facial tissue in a cube box
  • Pack includes 4 Cubes (56 Tissues per Cube) of Puffs Ultra Soft & Strong Facial Tissues
5.99 $5.99
4/Pack
Get it by Thu, Oct 25
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Puffs® Plus Lotion Facial Tissues, 1-Ply, 56 Sheets/Box, Cube Box, 4/Pack (34899)
Item: 1917288 / Model : 34899
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  • Single-ply tissues
  • 4 boxes/pack
  • 8 2/5" L cube box
5.99 $5.99
4/Pack
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Angel Soft Ultra Professional Series® 2-Ply Facial Tissue by GP PRO, Flat Box, 125 Sheets/Box, 10 Boxes/Carton (4836014)
Item: 1279018 / Model : 4836014
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  • 125 sheets per box
  • 2-ply
  • 10 boxes per carton
22.31 $22.31 27.89 $27.89
10/Carton
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Price: $27.89
Instant Savings: -$5.58
$22.31*
10/Carton
*Price after savings
Staples Facial Tissues Cube Box, 2-Ply, 95 Sheets/Box, Single Box
Item: 24322420 / Model : 53222
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  • 2-Ply Facial Tissue
  • Strong and Absorbent
  • Sold in 1/PK
1.29 $1.29
Each
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Kleenex® Flat Box Soft Facial Tissues, 2-Ply, White, 100 Tissues per Box (KC21400)
Item: 378137 / Model : 21400
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  • Two-ply tissue for superior strength and plush softness
  • One box
  • White tissues turn to peach-colored when it's time to replace the box
1.79 $1.79
100/Box
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Sustainable Earth by Staples® facial tissue, 2-ply, cube box, 85 sheets/bx, 6 bx/case (SEB20193-CC)
Item: 887833 / Model : 410837
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  • 2-Ply
  • 6 Boxes/Case
  • Sheet size: 9" x 7.8"
11.49 $11.49
6 Boxes/Case
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Kleenex 2-Ply Everyday Facial Tissues, 160 Tissues per Flat Box, 3 Pack + 24ct. Wet Wipes Bonus (48893)
Item: 24296570 / Model : 48893
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  • Kleenex Everyday Tissues offer gentle care for face and hands
  • Rely on durable; 2-ply thickness paper tissue sheets
  • Absorbent; disposable facial tissues lock in moisture
4.99 $4.99
Each
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Staples Facial Tissues Flat Box, 2-Ply, 160 Sheets/Box, Single Box
Item: 24322421 / Model : 53223
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  • 2-Ply Facial Tissue
  • Strong and Absorbent
  • Sold in 1/PK
1.29 $1.29
Each
Get it by Thu, Oct 25
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Puffs® Cube Ultra Soft 2-Ply Facial Tissues, 56/Box
Item: 1560503 / Model : 35038
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  • Air-Fluffed™ pillows for a more cushiony feel
  • Great for every room in the house
  • Designed for everything your face has to face
2.09 $2.09
Each
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Kleenex® Boutique Facial Tissue, 2-Ply, White, 95 Tissues/Bx
Item: 477898 / Model : 21270
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  • Soft, strong and absorbent
  • Special feature lets you know when tissues are about to run out
  • The best image for your business
2.49 $2.49
95/Box
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Kleenex Go Pack Facial Tissues, 3-Ply, 3 Pouches/Pack, 10 Sheets/Pouch
Item: 161851 / Model : 11976
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  • 3 pouches per pack
  • 10 tissues per pouch
  • 3-ply white
3.49 $3.49 3.79 $3.79
Pack
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Price: $3.79
Instant Savings: -$0.30
$3.49*
Pack
*Price after savings
Puffs Ultra Soft Facial Tissues, 56 Tissues/Cube, 24/CT
Item: 2676177 / Model : 35295CT
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  • Facial Tissue
  • Puffs Ultra Soft and Strong is our most comforting lotionless facial tissue in a cube box
  • Pack includes 4 Cubes (56 Tissues per Cube) of Puffs Ultra Soft & Strong Facial Tissues
31.29 $31.29
24/Carton
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Kleenex Boutique Facial Tissues, 2-Ply, 3/Pack
Item: 483115 / Model : 21200
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  • C-fold sheets
  • White
  • 3/pack
7.39 $7.39
3/Pack
Get it by Thu, Oct 25
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Staples Facial Tissues Flat Box, 2-Ply, 160 Sheets/Box, 36 Boxes/Case
Item: 24322423 / Model : 53223CT
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  • 2-Ply Facial Tissue
  • Strong and Absorbent
  • 36 flat boxes/case
43.99 $43.99
36/Carton
Get it by Thu, Oct 25
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Kleenex multicare Facial Tissues; 80 Tissues per Box, 4 pack
Item: 2637745 / Model : 46356
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  • Rely on durable; 2-ply thickness paper tissue sheets
  • Absorbent; disposable facial tissues lock in moisture
  • Tissue boxes with 80 tissues per box
5.99 $5.99
4/Pack
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Envision® 2-Ply Facial Tissues by GP PRO, White, 100 Sheets/Box, 30 Boxes/Case (47410)
Item: 493465 / Model : 47410
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  • 100 tissues per box
  • 2-ply for increased thickness
  • 30 boxes per pack for long-term use
44.49 $44.49
30/Carton
Get it by Thu, Oct 25
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Staples Facial Tissues Single Cube Box, 2-Ply, 95 Sheets/Box, 36 Boxes/Case
Item: 24322422 / Model : 53222CT
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  • 2-Ply Facial Tissue
  • Strong and Absorbent
  • 36 cube boxes/case
44.99 $44.99
36/Carton