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Seal fasteners of adjustment screws, countersunk head screws, set screws, collars, pulleys, and tool holders with the Loctite 243 Threadlocker. It is designed for filling the gaps in threaded fasteners measuring 0.25 inch to 0.75 inch in diameter. This medium strength threadlocker provides controlled lubrication and prevents screws from loosening due to shock or vibrations. With a curing time of 10 minutes, this threadlocker works at temperature range of -65 deg. F to 360 deg. F.