Sponsored Products
Logitech M720 Triathlon Wireless Ergonomic Optical Mouse, Black (910-004790)~#|#~5AB2B329-41CF-4292-82755E6648820B87_sc7
Logitech M720 Triathlon Wireless Ergonomic Optical Mouse, Black (910-004790)~#|#~6E855D99-65BD-490D-A9014F8319AB3455_sc7
Item # : 2392528
Model # : 910-004790
  • Wireless, multi-device mouse for convenience
  • Bluetooth and USB connectivity offers flexibility
Price is $44.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Logitech ERGO M575 Wireless Ergonomic Trackball Mouse, Black (910-007026)~#|#~90AF459C-D9FF-4770-8A3DFBAE7950B2C4_sc7
Logitech ERGO M575 Wireless Ergonomic Trackball Mouse, Black (910-007026)~#|#~24A7A966-96C8-42C9-817BCE7A8DC7811A_sc7
Item # : 24460735
Model # : 910-007026
WORK IN YOUR COMFORT ZONE
  • Less Movement, More Comfort: The sculpted shape of the ERGO M575S wireless trackball mouse keeps your hand relaxed for hours of smooth, precise tracking with thumb control - now with quiet clicks
  • 25% less muscle strain in your forearm: This wireless ergonomic mouse has been developed with Logi Ergo Lab experts, user-tested and certified by ergonomists for all-day comfort
Price is $49.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Logitech MX Ergo S Advanced Wireless Ergonomic Trackball Mouse, Black (910-005178)~#|#~sp162863831_sc7
Logitech MX Ergo S Advanced Wireless Ergonomic Trackball Mouse, Black (910-005178)~#|#~sp162863889_sc7
Item # : 2764655
Model # : 910-007247
Elevate your comfort and precision
  • Advanced thumb control: The MX Ergo S Advanced wireless trackball mouse gives more control with less movement; switch between speed and high-precision tracking at the tap of a button
  • 20-degree tilt: A wireless ergonomic mouse with a tilt angle for better forearm posture, reducing muscle strain by 27% (1); now with 80% quieter clicks
Price is $119.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Logitech M705 Marathon Wireless Ergonomic Optical USB Mouse, Charcoal (910-001935)~#|#~141FEADB-0A7D-4458-8914F05C3E840A23_sc7
Logitech M705 Marathon Wireless Ergonomic Optical USB Mouse, Charcoal (910-001935)~#|#~692CE431-845C-41E0-B4139CE75D185072_sc7
Item # : 870571
Model # : 910-001935
The precision mouse that’s built for the long haul, with a sculpted shape, dual-mode scrolling, and more control so you can tackle any task.
  • 3-Year Battery Life: This wireless optical mouse features an auto-sleep power-saving mode and on/off switch so you can enjoy up to 3 years (1) of charge on 2 AA batteries
  • Designed for Comfort: Sculpted with comfort in mind, your wireless computer mouse follows the natural curve of your right hand, and all controls are within your reach
Price is $39.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Staples TECH Wireless Ergonomic Curved Optical USB Mouse, Black (ST62599)~#|#~E21489FD-F764-4C90-92C265E7B1FE3B28_sc7
Staples TECH Wireless Ergonomic Curved Optical USB Mouse, Black (ST62599)~#|#~0C0DB036-3504-4B04-89726D10A306DEBB_sc7
20% off of Staples TECH Wireless Ergonomic Curved Optical USB Mouse, Black (ST62599)
Item # : 24596651
Model # : ST62599
The Staples TECH Wireless Optical Ergonomic Mouse gives you comfort and performance
  • Ergonomic design to minimize discomfort
  • Made to fit most hand sizes
Price is $13.11, Regular price was $16.39, You save 20%
Next-Day Delivery by tomorrow
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Delton Ergonomic 12 Wireless Ergonomic Vertical Optical Gaming Mouse, Black (DMERG12-WB)~#|#~D03FAC66-AB29-4C98-91526B4C54A88B53_sc7
Delton Ergonomic 12 Wireless Ergonomic Vertical Optical Gaming Mouse, Black (DMERG12-WB)~#|#~37C456D2-5F15-46CC-A228ADBD9186B3FD_sc7
Item # : 24553378
Model # : DMERG12-WB
Reduce wrist strain and stay comfortable throughout your work day on nearly any surface with this Delton wireless ergonomic mouse.
  • Superior CMOS sensors make this optical mouse perfect for everyday use at home, in the office, or on the go
  • Works within a wireless range of up to 30' with the included 2.4GHz USB dongle
Price is $34.39
Delivery by Fri, May 16
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Delton S38 Ergonomic Vertical Optical USB Mouse, Black (DMS38-U)~#|#~49567425-4C46-4E7E-BA0BF17386854FC7_sc7
Delton S38 Ergonomic Vertical Optical USB Mouse, Black (DMS38-U)~#|#~9374D591-3727-4119-8EE0F67D6EEB9559_sc7
Item # : 24627411
Model # : DMS38-U
No reviews yet
Stay efficient with Delton wired ergonomic computer mouse, featuring a vertical design for natural wrist positioning, customizable DPI settings for precision, and noiseless buttons for quiet, seamless operation.
  • Delton S38 wired ergonomic pc mouse features a vertical design that promotes natural wrist positioning
  • Specifically designed to alleviate wrist strain, this computer mouse supports healthier arm and hand motions recommended by rheumatologists.
Price is $37.89
Free delivery by Fri, May 16
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Logitech Signature M650 L Wireless Ergonomic Left Handed Optical Mouse, Graphite (910-006234)~#|#~2FE85650-C31F-4DEC-8F5EAB92029AA355_sc7
Logitech Signature M650 L Wireless Ergonomic Left Handed Optical Mouse, Graphite (910-006234)~#|#~945228AD-F884-4579-B2377B7095A97013_sc7
Item # : 24516903
Model # : 910-006234
SCROLLS SMARTER. FITS BETTER.
  • Scroll smarter: With Logitech Signature M650 Wireless Mouse you get line-by-line precision for documents and super-fast scrolling for long web pages; simply switch modes with a flick of the SmartWheel
  • Left handed design: This comfortable full size mouse is designed for larger hands, for the optimal fit for left handed users
Price is $39.99
Free delivery by Fri, May 16
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Logitech Signature M650 Wireless Ergonomic Optical USB Mouse, Rose (910-006251)~#|#~07A8ED9A-E25B-4DA6-A3CD36099F29584C_sc7
Logitech Signature M650 Wireless Ergonomic Optical USB Mouse, Rose (910-006251)~#|#~166B7ADB-A34E-4734-B1CEC66F1506DDCD_sc7
Item # : IM19VP958
Model # : 910-006251
SCROLLS SMARTER. FITS BETTER.
  • Scroll smarter: With Logitech Signature M650 Wireless Mouse you get line-by-line precision for documents and super-fast scrolling for long web pages; simply switch modes with a flick of the SmartWheel
  • The optimal fit for your hand: This comfortable mouse is designed for small-to-medium sized hands, for the optimal fit
Price is $40.18
Free delivery by Fri, May 16
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Contour Design RollerMouse Pro3 Ergonomic Ambidextrous Rollerbar USB Mouse, Black (RM-PRO3)~#|#~sp37727950_sc7
Contour Design RollerMouse Pro3 Ergonomic Ambidextrous Rollerbar USB Mouse, Black (RM-PRO3)~#|#~sp37727954_sc7
Item # : 2756654
Model # : RM-PRO3
Find a new way to interact with your computer with this Contour Design RollerMouse Pro3 mouse alternative.
  • Wired connectivity for accuracy and dependability
  • Rollerbar mouse for improved precision
Price is $279.00
Free delivery 
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Delton Ergonomic 12 Wireless Ergonomic Vertical Optical Gaming Mouse, Black (DMERG12-WR )~#|#~2694E632-14D9-4D52-B7857BDF2763B66C_sc7
Delton Ergonomic 12 Wireless Ergonomic Vertical Optical Gaming Mouse, Black (DMERG12-WR )~#|#~B9C8957D-F826-49DC-872C0CA97126BED1_sc7
Item # : 24553380
Model # : DMERG12-WR
Reduce wrist strain, stay comfortable all day, and enjoy precise tracking on nearly any surface with this Delton Ergonomic wireless mouse.
  • Superior CMOS sensors make this optical mouse perfect for everyday use at home, in the office, or on the go
  • Works within a wireless range of up to 30' with the included 2.4GHz USB dongle
Price is $37.79
Free delivery by Fri, May 16
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Logitech MX Master 2S Wireless Ergonomic Laser Mouse, Graphite (910-005965)~#|#~sp117042503_sc7
Logitech MX Master 2S Wireless Ergonomic Laser Mouse, Graphite (910-005965)~#|#~sp117042502_sc7
Item # : IM18GY950
Model # : 910-005965
The MX MASTER 2S Bluetooth Edition is the ultimate precision mouse for power users.
  • Laser mouse allows you to have complete control over cursor movement
  • Take this reliable wireless mouse anywhere
Price is $119.09
Free delivery by Fri, May 16
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Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)~#|#~sp147267338_sc7
Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)~#|#~sp147267337_sc7
Item # : 24450019
Model # : 910-005790
Make the most of your game time with G203 gaming mouse, featuring LIGHTSYNC technology, a gaming-grade sensor and a classic 6-button design. Light up your game … and your desk.
  • Choose from vibrant animations, game- and media-driven settings, or program your own from approximately 16.8 million colors.
  • Pick one color, blend three, choose a fun animation preset, or make your own. The choice is yours! You can even sync your mouse with other Logitech G LIGHTSYNC gear so it’s a perfect match.
Price is $34.99
Delivery by Mon, May 19
1-hr pickup
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Adesso iMouse E1 Ergonomic Vertical Optical USB Mouse, Glossy Black~#|#~m000496438_sc7
Item # : IM1TG7897
Model # : IMOUSE E1
Adesso Vertical ergonomic illuminated mouse in black color has quickly adjust DPI resolution for a faster response and has optical sensor that manage the mouse precisely on point.
  • Glossy black, LED color: Blue
  • Designed with a vertical orientation and a contoured shape that provides a uniquely comfortable user experience
Price is $35.99
Free delivery by Mon, May 19
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Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Pale Gray (910-006570)~#|#~A9283F17-9F18-43BE-B4542F3E4D83BC18_sc7
Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Pale Gray (910-006570)~#|#~CEF56B21-D442-4D40-9ACCA86DAC186771_sc7
Item # : 24532676
Model # : 910-006570
  • Optical mouse perfect for everyday use at home or in the office
  • Take this reliable wireless mouse anywhere with 32.81' wireless operating distance
Price is $119.99
Free delivery by Fri, May 16
1-hr pickup
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Delton T100 Wireless Ergonomic Trackball USB Mouse, Black (DMST100-WB)~#|#~73BD21BA-45FF-4EBC-B1B9DBEDDF0E7EE3_sc7
Delton T100 Wireless Ergonomic Trackball USB Mouse, Black (DMST100-WB)~#|#~D1BDB619-3327-431F-A2D135C287F622BD_sc7
Delton T100 Wireless Ergonomic Trackball USB Mouse, Black (DMST100-WB) is New at Staples
Item # : 24628063
Model # : DMST100-WB
No reviews yet
Experience ultimate control and comfort with Delton vertical trackball mouse, designed for smooth, uninterrupted performance whether you're working or gaming.
  • Delton T100 wireless trackball mouse features a semi-vertical design for a comfortable grip, fitting all hand shapes and reducing strain during extended use.
  • This sub wireless mouse offers versatile connectivity with 2.4G wireless technology, Bluetooth support, and a USB dongle for an effortless plug-and-used setup.
Price is $86.59
Free delivery by Fri, May 16
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Lenovo 300 Ergonomic Ambidextrous USB Mouse, Black (GX30M39704)~#|#~sp138450164_sc7
Item # : IM15JV332
Model # : GX30M39704
  • Wired connectivity for accuracy and dependability
  • Ambidextrous design allows everybody to use one versatile mouse
Price is $7.49
Delivery by Fri, May 16
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Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020)~#|#~sp132272604_sc7
Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020)~#|#~sp132272603_sc7
Item # : 24489781
Model # : 910-006020
Travel Mouse - Optical - Wireless - Radio Frequency - 2.40 GHz - Lilac - 12000 dpi - 6 Button(s)
  • HERO Sensor - Next-generation HERO sensor delivers incredible performance and up to 10x the power efficiency over previous generations. HERO is an optical sensor capable of exceptional accuracy and responsiveness with 400 IPS precision and up to 12,000 DPI sensitivity.
  • LIGHTSPEED Wireless - Ultra-fast LIGHTSPEED Wireless technology gives you a lag-free gaming experience. G305 delivers incredible responsiveness and reliability with a super fast 1 ms report rate for competition-level performance.
Price is $51.39
Free delivery by Fri, May 16
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Logitech Ergo M575S Wireless Ergonomic Trackball Mouse, Off-White/Blue (910-007028)~#|#~A85DCD19-667B-4814-B7703D0BDE0C523B_sc7
Logitech Ergo M575S Wireless Ergonomic Trackball Mouse, Off-White/Blue (910-007028)~#|#~60C072B4-2FDE-4B7B-9F8F7C91AE938E78_sc7
Item # : IM1NP4549
Model # : 910-007028
No reviews yet
  • The Ergo M575S Wireless Trackball employs Logitech Advanced Optical Tracking technology for precise cursor control and smooth navigation, making it ideal for productivity tasks while also suitable for casual gaming due to its responsive tracking and customizable buttons, although it is not specifically designed for competitive gaming.
  • It is a wireless trackball mouse, offering both Bluetooth and USB connectivity options for versatile usage.
Price is $50.24
Free delivery by Fri, May 16
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Logitech Lift for Mac Wireless Ergonomic Vertical Optical USB Mouse, White (910-006471)~#|#~06220A2A-39F8-4A67-B672286E62996B94_sc7
Logitech Lift for Mac Wireless Ergonomic Vertical Optical USB Mouse, White (910-006471)~#|#~DD139E04-DFF1-4115-92865B8B0E46E494_sc7
Item # : IM102PP61
Model # : 910-006471
Lift for Mac® Vertical Ergonomic Mouse is designed for Mac and made for your comfort.
  • Get comfy from first light to late night with this ergonomic mouse
  • Take this reliable wireless mouse anywhere
Price is $90.58
Free delivery by Fri, May 16
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Adesso iMouse T40 Wireless Ergonomic Ambidextrous Optical Mouse, Red/Black~#|#~m007167965_sc7
Item # : IM15KA517
Model # : IMOUSE T40
  • Enjoy the freedom of Radio Frequency wireless connectivity found in most Desktop Computers
  • Perform mousing with minimal hand movement or space by using trackball scroller
Price is $58.31
Free delivery by Fri, May 16
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Logitech Lift Wireless Ergonomic Vertical Optical USB Mouse, Graphite (910-006466)~#|#~76ED1A18-721F-4C0B-9420C05103C121C0_sc7
Logitech Lift Wireless Ergonomic Vertical Optical USB Mouse, Graphite (910-006466)~#|#~937FA99F-2B85-4E2C-B931602AC76751C5_sc7
Item # : IM100HA56
Model # : 910-006466
No reviews yet
  • Get comfy from first light to late night with this mouse in graphite color
  • Take this reliable wireless mouse anywhere
Price is $79.99
Free delivery by Fri, May 16
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Adesso iMouse G2 Ergonomic Ambidextrous Optical USB Mouse, Black~#|#~m006851930_sc7
Item # : IM19L0562
Model # : IMOUSE G2
No reviews yet
  • Plug and play USB interface for a quick and perfect configuration
  • Optical LED for smoother movement and hassle-free performance
Price is $29.29
Delivery by Fri, May 16
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CODi 6D Wireless Ergonomic Vertical Optical USB Mouse, Black (A05002)~#|#~sp247878433_sc7
CODi 6D Wireless Ergonomic Vertical Optical USB Mouse, Black (A05002)~#|#~sp247878432_sc7
Item # : IM1JQ6772
Model # : A05002
No reviews yet
CODi 6D Wireless Multi-Device Ergonomic Mouse
  • ERGONOMIC DESIGN: Ergonomically designed to allow the wrist to be in a neutral position, reducing strain and discomfort.
  • Up to 32.8ft (10m) operational distance
Price is $34.99
Delivery by Fri, May 16
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Razer Basilisk V3 Ergonomic Optical USB Gaming Mouse, Black (RZ0104000100R3)~#|#~75692D19-8D1B-440E-BE4F2862EB848292_sc7
Razer Basilisk V3 Ergonomic Optical USB Gaming Mouse, Black (RZ0104000100R3)~#|#~4284EF50-DC3B-4817-B745D62612DDB21B_sc7
Item # : 24536636
Model # : RZ0104000100R3
  • Fast and precise optical gaming mouse for everyday use at home or in the office
  • Wired connectivity for accuracy and dependability
Price is $69.99
Free delivery by Thu, May 22
1-hr pickup
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Adesso iMouse M300W Wireless Ergonomic Ambidextrous Optical Mouse, White~#|#~m000073235_sc7
Item # : IM1RG0786
Model # : IMOUSE M300W
The Adesso IMOUSE M300W White Optical Mouse comes with a wireless interface that ensures responsive cursor control.
  • Optical mouse for everyday use in commercial or personal environments
  • Wireless connectivity for lag-free usage
Price is $25.49
Delivery by Mon, May 19
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Anyone who spends a lot of time on a computer can benefit from using an ergonomic mouse. These innovative devices allow the hand to rest in a healthy position, reducing strain and preventing repetitive stress injuries so users can work or play all day comfortably.

Today's computer users have a wide selection of styles to choose from. Wireless and compact designs deliver healthy posture without tangled cords. Ambidextrous models are comfortable for right or left handed use, and alternative devices accommodate users who use their fingers, palms or a stylus to control the pointer.

Comfortable Hand Position for Hours of Work or Play

There are a variety of shapes and sizes of ergonomic mice to choose from including vertical, handshoe and fingertip. Vertical designs allow users to navigate with their arm instead of the wrist reducing wrist pressure that is associated with carpal tunnel syndrome. Handshoe shaped mice are contoured to form-fit the hand, so fingers rest comfortably when not in use and clicking requires minimal motion. Fingertip models require no wrist or arm movement. Instead, they are controlled using quick finger movements in much the same way as writing.

Wireless Ergonomic Mice Offer Freedom of Movement

Wireless mice are a good choice for users who have small working spaces or who travel a lot. They are connected to the computer using Bluetooth or a USB dongle instead of a cord. Wireless designs are also convenient for conference room systems, classrooms and media centers, where users are standing or sitting a significant distance from the computer.

Choose Ambidextrous Models for Left Hand or Right Hand Use

Ambidextrous mice are comfortable for both right handed and left handed use. They are popular with gamers who like to switch hands and artists who illustrate with either hand. Ambidextrous styles are also a good choice for public terminals and shared workspaces such as conference rooms, touchdown spaces and co-op offices.

Compact Designs Fit Easily in Small Bags

For productivity on the go, choose compact devices that travel well. Handshoe shaped mice are flat and stow easily in backpacks and luggage. For an even smaller ergonomic mouse, choose a fingertip model. These small designs deliver healthy hand and wrist posture without the bulky design.

Alternative Designs Deliver a Range of Benefits

Alternative ergonomic mice offer function without the traditional mouse shape. Common alternative designs include touchpads, central pointing devices and trackballs. Touchpads and tablets allow users to navigate, draw and click with the touch of their fingers or with a stylus. Trackballs are popular among gamers, drafters, animators and engineers. They feature fast and precise cursor and pointer movement since users roll the ball instead of moving the entire mouse.

To find the best ergonomic mouse, consider the needs of the user. For busy professionals and students who need mobility and freedom of movement, look for wireless and compact designs. Most models come in left handed or right handed versions and ambidextrous models are a good choice for shared terminals and public computers. Alternative models are ideal for specialized users such as illustrators and engineers or for users who require special accommodations.