Logitech Signature M550 L Wireless Ergonomic Ambidextrous Optical Mouse, Blue (910-006794)~#|#~2774352E-BAF7-4C19-94D99E593458C769_sc7Logitech Signature M550 L Wireless Ergonomic Ambidextrous Optical Mouse, Blue (910-006794)~#|#~D84618F1-AF14-4218-971DBD9CCA5E33A2_sc7
Item: IM1NK9456
Model: 910-006794
No reviews yet
Price is $29.99
Delivery by Mon, Sep 22
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Lenovo 300 Ergonomic Ambidextrous USB Mouse, Black (GX30M39704)~#|#~sp138450164_sc7
Item: IM15JV332
Model: GX30M39704
Price is $7.46
Delivery by Tue, Sep 23
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Logitech Signature M650 L Wireless Ergonomic Left Handed Optical Mouse, Graphite (910-006234)~#|#~2FE85650-C31F-4DEC-8F5EAB92029AA355_sc7Logitech Signature M650 L Wireless Ergonomic Left Handed Optical Mouse, Graphite (910-006234)~#|#~945228AD-F884-4579-B2377B7095A97013_sc7
Item: 24516903
Model: 910-006234
Price is $39.99
Free delivery by Mon, Sep 22
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HyperX Pulsefire Haste 2 Ergonomic Optical Gaming Mouse, Black (6N0A7AA)~#|#~C361D652-C658-4663-BB7B97100BC12DDE_sc7HyperX Pulsefire Haste 2 Ergonomic Optical Gaming Mouse, Black (6N0A7AA)~#|#~B2AC2CA8-9873-451C-909828BCD126DE54_sc7
HyperX Pulsefire Haste 2 Ergonomic Optical Gaming Mouse, Black (6N0A7AA) is In-store only
Item: 24579145
Model: 6N0A7AA
Price is $59.99
30-min pickup
SteelSeries AEROX 3 Wireless Ergonomic Optical USB Gaming Mouse, Onyx (62612)~#|#~69DCB5D4-216E-4975-910C1B3BE64BAFA0_sc7SteelSeries AEROX 3 Wireless Ergonomic Optical USB Gaming Mouse, Onyx (62612)~#|#~45C5046D-ED72-4A88-B472B7FB130D4437_sc7
Item: IM100GF05
Model: 62612
No reviews yet
Price is $120.65
Free delivery by Mon, Sep 22
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Adesso iMouse E1 Ergonomic Vertical Optical USB Mouse, Glossy Black~#|#~m000496438_sc7
Item: IM1TG7897
Model: IMOUSE E1
Price is $34.76
Delivery by Tue, Sep 23
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Kensington® K72424WW Wireless Optical Mouse (K72424AMA)~#|#~m006965524_sc7
Kensington Pro Fit Wireless Ergonomic Optical Mouse, Emerald Green (PX7393) is New at Staples
Item: IM1PX7393
Model: K72424AMA
No reviews yet
Price is $22.16
Delivery by Tue, Sep 23
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Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)~#|#~sp147267338_sc7Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)~#|#~4CA76A13-9D01-4413-A5EA6675CE2580A0_sc7
8% off of Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)
Item: 24450019
Model: 910-005790
Price is $31.99, Regular price was $34.99, You save 8%
Delivery by Tue, Sep 23
30-min pickup
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Contour Design RollerMouse Red Plus Wireless Ergonomic Ambidextrous Rollerbar USB Mouse, Black (CDRMRED10210)~#|#~195B3F0B-7497-4DA1-AEEA0B94C1AB6E25_sc7Contour Design RollerMouse Red Plus Wireless Ergonomic Ambidextrous Rollerbar USB Mouse, Black (CDRMRED10210)~#|#~3666422C-5EDF-45A3-B1296D2008E97B80_sc7
Contour Design RollerMouse Red Plus Wireless Ergonomic Ambidextrous Rollerbar USB Mouse, Black (CDRMRED10210) is New at Staples
Item: IM1JW7933
Model: CDRMRED10210
No reviews yet
Price is $454.00
Free delivery by Wed, Sep 24
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Verbatim Notebook Ergonomic Ambidextrous Optical USB Mouse, Blue (99743)~#|#~sp21665044_sc7Verbatim Notebook Ergonomic Ambidextrous Optical USB Mouse, Blue (99743)~#|#~sp21665041_sc7
Item: IM19U6168
Model: 99743
No reviews yet
Price is $11.33
Delivery by Mon, Sep 22
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Kensington Expert Ergonomic Ambidextrous Optical USB Mouse, Black (K64325)~#|#~m001383899_sc7
Item: IM1893991
Model: K64325
No reviews yet
Price is $100.19
Free delivery by Wed, Sep 24
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3Dconnexion SpaceMouse Ergonomic USB Mouse, Black (3DX-700040)~#|#~s0772983_sc73Dconnexion SpaceMouse Ergonomic USB Mouse, Black (3DX-700040)~#|#~s0772983_sc7
Item: IM1KV6318
Model: 3DX-700040
Price is $408.09
Free delivery by Wed, Sep 24
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SteelSeries Rival 3 Gen 2 Wireless Ergonomic Optical Bluetooth & USB Mouse, White (62688)~#|#~DC07FE2D-01CB-4666-9C1BD2D4C5EA6146_sc7SteelSeries Rival 3 Gen 2 Wireless Ergonomic Optical Bluetooth & USB Mouse, White (62688)~#|#~D01C523A-E265-4C5F-B6CF2F25D63CAA97_sc7
SteelSeries Rival 3 Gen 2 Wireless Ergonomic Optical Bluetooth & USB Mouse, White (62688) is New at Staples
Item: IM1SR4475
Model: 62688
No reviews yet
Price is $59.99
Free delivery by Wed, Sep 24
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SteelSeries Rival 3 Gen 2 Wireless Ergonomic Ambidextrous Optical Gaming Mouse, Black (62687)~#|#~2B8B6A6A-205F-4C65-8997D1CF71070415_sc7SteelSeries Rival 3 Gen 2 Wireless Ergonomic Ambidextrous Optical Gaming Mouse, Black (62687)~#|#~C90FFFE3-FDF9-42C5-885A30A620599182_sc7
SteelSeries Rival 3 Gen 2 Wireless Ergonomic Ambidextrous Optical Gaming Mouse, Black (62687) is New at Staples
Item: IM1SR4473
Model: 62687
No reviews yet
Price is $59.99
Free delivery by Wed, Sep 24
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Logitech G305 Lightspeed Wireless Optical Gaming Mouse, White (910-005289)~#|#~4F8A4AA5-2C5C-4926-9D67CE666CB842C8_sc7Logitech G305 Lightspeed Wireless Optical Gaming Mouse, White (910-005289)~#|#~6C2697DC-2256-4433-A2345DCC1542F57D_sc7
Item: 24489805
Model: 910-005289
Price is $59.99
Free delivery by Tue, Sep 23
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Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Blue (99766)~#|#~sp14904615_sc7Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Blue (99766)~#|#~sp14904614_sc7
Verbatim Commuter Series Wireless Notebook Optical Mouse, Matte Blue (99766) is New at Staples
Item: IM19U6592
Model: 99766
No reviews yet
Price is $15.99
Delivery by Mon, Sep 22
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Logitech Lift for Business Wireless Ergonomic Vertical Optical Bluetooth & USB Mouse, Off-White (910-006469)~#|#~74C4B1B9-8684-463A-BCFABAA8FC7E38E1_sc7Logitech Lift for Business Wireless Ergonomic Vertical Optical Bluetooth & USB Mouse, Off-White (910-006469)~#|#~D3275A07-45E8-42EB-A3D7DB9BD72B4EEE_sc7
Item: 24531607
Model: 910-006469
Price is $79.99
Free delivery by Mon, Sep 22
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Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Red (99767)~#|#~sp14904620_sc7Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Red (99767)~#|#~sp14904619_sc7
Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Red (99767) is New at Staples
Item: IM19U6593
Model: 99767
Price is $12.99
Delivery by Mon, Sep 22
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Lenovo Professional Wireless Ergonomic Ambidextrous Laser USB Mouse, Black (4X30H56886)~#|#~m006975368_sc7
Lenovo Professional Wireless Ergonomic Ambidextrous Laser USB Mouse, Black (4X30H56886) is New at Staples
Item: IM12CV970
Model: 4X30H56886
Price is $34.64
Delivery by Tue, Sep 23
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Logitech Signature M650 L for Business Wireless Ergonomic Optical USB Mouse, Graphite (910-006346)~#|#~sp161540016_sc7Logitech Signature M650 L for Business Wireless Ergonomic Optical USB Mouse, Graphite (910-006346)~#|#~sp161540015_sc7
Item: IM19VP966
Model: 910-006346
No reviews yet
Price is $79.99
Free delivery by Tue, Sep 23
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Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Black (99765)~#|#~sp14904610_sc7Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Black (99765)~#|#~sp14904609_sc7
Verbatim Commuter Wireless Ergonomic Ambidextrous Optical USB Mouse, Black (99765) is New at Staples
Item: IM19U6591
Model: 99765
Price is $15.59
Delivery by Tue, Sep 23
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Logitech Signature M550 Wireless Ergonomic Ambidextrous Optical Mouse, Rose (910-006593)~#|#~7CC97F95-F413-4589-8338E4FDEA565B8A_sc7Logitech Signature M550 Wireless Ergonomic Ambidextrous Optical Mouse, Rose (910-006593)~#|#~6A2951D7-F9AD-48FD-9AB68EF03FF4A758_sc7
Item: IM1NK9455
Model: 910-006593
No reviews yet
Price is $33.72
Delivery by Mon, Sep 22
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Incase Designed by Microsoft Bluetooth Ergonomic Wireless Mouse, Pastel Blue (222-00049)~#|#~1E45FF65-65A6-4218-A2674D86F4CC9768_sc7Incase Designed by Microsoft Bluetooth Ergonomic Wireless Mouse, Pastel Blue (222-00049)~#|#~5770494D-B072-4060-BAC6A6766E064488_sc7
Item: 24619786
Model: 222-00049
No reviews yet
Price is $59.99
Free delivery 
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Incase Designed by Microsoft Bluetooth Ergonomic Wireless Mouse, Glacier (222-00017)~#|#~7D875D0B-047C-4BA3-9F96EBEAB81E61E2_sc7Incase Designed by Microsoft Bluetooth Ergonomic Wireless Mouse, Glacier (222-00017)~#|#~D1F9114D-6B59-452D-9D9A0527E014F5D1_sc7
Item: 24619787
Model: 222-00017
No reviews yet
Price is $59.99
Free delivery 
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Logitech Signature Plus M750 Wireless Ergonomic Curved Ambidextrous Optical Mouse, Graphite (910-007510)~#|#~0AB6D004-C5D2-468C-8DD97940676D8E6F_sc7Logitech Signature Plus M750 Wireless Ergonomic Curved Ambidextrous Optical Mouse, Graphite (910-007510)~#|#~A9822E04-3FF3-4C36-B8E3F7A035A9338F_sc7
Logitech Signature Plus M750 Wireless Ergonomic Curved Ambidextrous Optical Mouse, Graphite (910-007510) is New at Staples
Item: IM1SE5028
Model: 910-007510
Price is $50.27
Free delivery by Mon, Sep 22
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Logitech Pro X Superlight 2 Dex Wireless Ergonomic Optical Gaming Mouse, Black (910-007328)~#|#~6BA994E3-1DDB-497E-A40EA31CCE7AEF96_sc7Logitech Pro X Superlight 2 Dex Wireless Ergonomic Optical Gaming Mouse, Black (910-007328)~#|#~B455148E-F4C5-4CBB-BE0A5B941D737E8B_sc7
Item: IM1NP4550
Model: 910-007328
No reviews yet
Price is $250.44
Free delivery by Tue, Sep 23
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Adesso iMouse Ergonomic Vertical Optical USB Mouse, Black (IMOUSE V3-TAA)~#|#~D151E339-A514-43DF-BB8B0A5013EF8C0C_sc7Adesso iMouse Ergonomic Vertical Optical USB Mouse, Black (IMOUSE V3-TAA)~#|#~11D7E945-419C-4670-B330223CB593F515_sc7
Adesso iMouse Ergonomic Vertical Optical USB Mouse, Black (IMOUSE V3-TAA) is New at Staples
Item: IM1JV3391
Model: IMOUSE V3-TAA
No reviews yet
Price is $50.19
Free delivery by Mon, Sep 22
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Adesso iMouse E10 Wireless Ergonomic Vertical Optical USB Mouse, Black~#|#~sp41688013_sc7Adesso iMouse E10 Wireless Ergonomic Vertical Optical USB Mouse, Black~#|#~sp41688012_sc7
Item: IM1TG7898
Model: IMOUSE E10
Price is $48.20
Free delivery by Mon, Sep 22
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Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Sheer Dream (910-007283)~#|#~F6405455-ECC2-4EE7-B5D5FD8947EAD13B_sc7Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Sheer Dream (910-007283)~#|#~98D3CE9A-069B-4571-8CDA81E2D50D2667_sc7
Item: IM1KS0742
Model: 910-007283
No reviews yet
Price is $22.99
Delivery by Tue, Sep 23
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Kensington Pro Fit Ergonomic Optical USB Mouse, Black (K72369US)~#|#~m001386653_sc7Kensington Pro Fit Ergonomic Optical USB Mouse, Black (K72369US)~#|#~s0505900_sc7
Kensington Pro Fit Ergonomic Optical USB Mouse, Black (K72369US) is Out of stock
Item: IM1GU1149
Model: K72369US
No reviews yet
Price is $43.19
Verbatim USB-C Wireless Blue LED 70247 Mouse, Teal~#|#~sp78730394_sc7Verbatim USB-C Wireless Blue LED 70247 Mouse, Teal~#|#~sp78730393_sc7
Verbatim USB-C Wireless Blue LED 70247 Mouse, Teal is Out of stock
Item: IM16YP097
Model: 70247
Price is $23.30
Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020)~#|#~D108F7C1-397B-4F02-9E503C29F5279CD0_sc7Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020)~#|#~9602D753-EE7F-4345-B5265DBB441A1C2F_sc7
Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020) is Out of stock
Item: 24489781
Model: 910-006020
Price is $59.99
HP 150 Wireless Ergonomic Optical Mouse, Black (2S9L1AA)~#|#~AF3FAD2C-1BDE-4E39-BB3E607D020C3850_sc7HP 150 Wireless Ergonomic Optical Mouse, Black (2S9L1AA)~#|#~1D9F3D87-4C05-4C6E-8C4767970F35FA74_sc7
HP 150 Wireless Ergonomic Optical Mouse, Black (2S9L1AA) is Out of stock
Item: 24577035
Model: 2S9L1AA
No reviews yet
Price is $21.09
Logitech Lift Wireless Ergonomic Vertical Left Handed Optical USB Mouse, Graphite (910-006467)~#|#~8DF41844-78A0-4327-B6495C481B2B27C6_sc7Logitech Lift Wireless Ergonomic Vertical Left Handed Optical USB Mouse, Graphite (910-006467)~#|#~34C65B22-622A-4C2A-A3F7F1F41E6AB04A_sc7
Logitech ERGO M575 Wireless Ergonomic Trackball Mouse, Graphite (910-006197) is Out of stock
Item: IM100HA57
Model: 910-006467
No reviews yet
Price is $89.99

Trending now

Anyone who spends a lot of time on a computer can benefit from using an ergonomic mouse. These innovative devices allow the hand to rest in a healthy position, reducing strain and preventing repetitive stress injuries so users can work or play all day comfortably.

Today's computer users have a wide selection of styles to choose from. Wireless and compact designs deliver healthy posture without tangled cords. Ambidextrous models are comfortable for right or left handed use, and alternative devices accommodate users who use their fingers, palms or a stylus to control the pointer.

Comfortable Hand Position for Hours of Work or Play

There are a variety of shapes and sizes of ergonomic mice to choose from including vertical, handshoe and fingertip. Vertical designs allow users to navigate with their arm instead of the wrist reducing wrist pressure that is associated with carpal tunnel syndrome. Handshoe shaped mice are contoured to form-fit the hand, so fingers rest comfortably when not in use and clicking requires minimal motion. Fingertip models require no wrist or arm movement. Instead, they are controlled using quick finger movements in much the same way as writing.

Wireless Ergonomic Mice Offer Freedom of Movement

Wireless mice are a good choice for users who have small working spaces or who travel a lot. They are connected to the computer using Bluetooth or a USB dongle instead of a cord. Wireless designs are also convenient for conference room systems, classrooms and media centers, where users are standing or sitting a significant distance from the computer.

Choose Ambidextrous Models for Left Hand or Right Hand Use

Ambidextrous mice are comfortable for both right handed and left handed use. They are popular with gamers who like to switch hands and artists who illustrate with either hand. Ambidextrous styles are also a good choice for public terminals and shared workspaces such as conference rooms, touchdown spaces and co-op offices.

Compact Designs Fit Easily in Small Bags

For productivity on the go, choose compact devices that travel well. Handshoe shaped mice are flat and stow easily in backpacks and luggage. For an even smaller ergonomic mouse, choose a fingertip model. These small designs deliver healthy hand and wrist posture without the bulky design.

Alternative Designs Deliver a Range of Benefits

Alternative ergonomic mice offer function without the traditional mouse shape. Common alternative designs include touchpads, central pointing devices and trackballs. Touchpads and tablets allow users to navigate, draw and click with the touch of their fingers or with a stylus. Trackballs are popular among gamers, drafters, animators and engineers. They feature fast and precise cursor and pointer movement since users roll the ball instead of moving the entire mouse.

To find the best ergonomic mouse, consider the needs of the user. For busy professionals and students who need mobility and freedom of movement, look for wireless and compact designs. Most models come in left handed or right handed versions and ambidextrous models are a good choice for shared terminals and public computers. Alternative models are ideal for specialized users such as illustrators and engineers or for users who require special accommodations.