Adesso iMouse A20 Wireless Ergonomic Vertical Optical Mouse, Black ~#|#~5AC8FA95-502A-4F95-A2B651DFA11B122B_sc7Adesso iMouse A20 Wireless Ergonomic Vertical Optical Mouse, Black ~#|#~803BED20-0D03-41AE-AECAF45DD18C20EE_sc7
Item: 24616744
Model: iMouse A20
No reviews yet
Price is $51.19
Free delivery 
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Kensington Pro Fit Wireless Ergonomic Optical Mouse, Black (K72424WW)~#|#~s0700679_sc7
Item: 74674
Model: KU7924
Price is $51.19
Free delivery by Wed, Apr 23
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Cherry MW 4500 Wireless Ergonomic Vertical Mouse, Black (JW-4500)~#|#~932E51DC-93FF-47E0-861269509FF9D615_sc7Cherry MW 4500 Wireless Ergonomic Vertical Mouse, Black (JW-4500)~#|#~674497AF-92A4-4895-B02CA8AF4A89AB80_sc7
Cherry MW 4500 Wireless Ergonomic Vertical Mouse, Black (JW-4500) is New at Staples
Item: 24599514
Model: JW-4500
No reviews yet
Price is $35.79
Free delivery by Wed, Apr 30
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Delton S22 Wireless Ergonomic Vertical Optical Mouse, Gray/Black (DMERGS22-WB)~#|#~ABD12782-D125-4548-98943E021B04FA01_sc7Delton S22 Wireless Ergonomic Vertical Optical Mouse, Gray/Black (DMERGS22-WB)~#|#~944E7227-1A55-4F3B-9A9546B078614C42_sc7
Item: 24586504
Model: DMERGS22-WB
No reviews yet
Price is $46.29
Free delivery by Fri, Apr 25
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Lexip NP93 Ergonomic Optical Gaming Mouse, Black (JVAPCM00446)~#|#~12713E45-8102-4A30-A60774013DFA0BBB_sc7Lexip NP93 Ergonomic Optical Gaming Mouse, Black (JVAPCM00446)~#|#~FD69A66F-0FA7-4020-9C182E8D7C3D44F1_sc7
Item: 24612360
Model: JVAPCM00446
No reviews yet
Price is $51.19
Free delivery by Tue, Apr 29
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Logitech Signature M550 L Wireless Ergonomic Ambidextrous Optical Mouse, Blue (910-006794)~#|#~2774352E-BAF7-4C19-94D99E593458C769_sc7Logitech Signature M550 L Wireless Ergonomic Ambidextrous Optical Mouse, Blue (910-006794)~#|#~D84618F1-AF14-4218-971DBD9CCA5E33A2_sc7
Item: IM1NK9456
Model: 910-006794
No reviews yet
Price is $159.99
Free delivery by Mon, Apr 28
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Adesso iMouse M300W Wireless Ergonomic Ambidextrous Optical Mouse, White~#|#~m000073235_sc7
Item: IM1RG0786
Model: IMOUSE M300W
Price is $26.99
Delivery by Fri, Apr 25
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Logitech Signature M650 Wireless Ergonomic Optical USB Mouse, Off-White (910-006252)~#|#~1ED01105-ADD9-4FC5-AF91D845B5E61772_sc7Logitech Signature M650 Wireless Ergonomic Optical USB Mouse, Off-White (910-006252)~#|#~FD05C924-22FD-418A-A2DA9E2B0341A93C_sc7
Item: IM19VP959
Model: 910-006252
No reviews yet
Price is $43.99
Free delivery by Mon, Apr 28
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Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Blue Galaxy (910-007282)~#|#~842A9B90-3F76-49E6-A66A34EB64189EFA_sc7Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Blue Galaxy (910-007282)~#|#~A4F2163B-9FA3-48EF-8B521101CBD39011_sc7
Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Blue Galaxy (910-007282) is New at Staples
44% off of Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Blue Galaxy (910-007282)
Item: IM1KS0741
Model: 910-007282
No reviews yet
Price is $14.99, Regular price was $26.83, You save 44%
Delivery by Fri, Apr 25
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Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Speckles (910-007281)~#|#~F43C400A-4C71-41BA-81E934A932A536B1_sc7Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Speckles (910-007281)~#|#~B0DBFC93-1066-4022-B31FAD0A74FF6971_sc7
Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Speckles (910-007281) is New at Staples
Item: IM1KS0743
Model: 910-007281
No reviews yet
Price is $158.96
Free delivery by Thu, Apr 24
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Cherry AK-PMH3 Ergonomic Ambidextrous Optical USB Mouse, White (AK-PMH3OB-US-W)~#|#~C9F5466B-084A-467B-A3F8662CE708CB96_sc7Cherry AK-PMH3 Ergonomic Ambidextrous Optical USB Mouse, White (AK-PMH3OB-US-W)~#|#~B0D25716-874C-45E9-8D4E4CADDC1F887C_sc7
Cherry AK-PMH3 Ergonomic Ambidextrous Optical USB Mouse, White (AK-PMH3OB-US-W) is New at Staples
Item: 24630807
Model: AK-PMH3OB-US-W
No reviews yet
Price is $64.99
Free delivery by Tue, Apr 29
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Urban Factory BIG CRAZY Ergonomic Ambidextrous Optical USB Mouse, Black (UBFBCM01UF)~#|#~sp179263779_sc7Urban Factory BIG CRAZY Ergonomic Ambidextrous Optical USB Mouse, Black (UBFBCM01UF)~#|#~sp179263774_sc7
Item: 24539493
Model: UBFBCM01UF
No reviews yet
Price is $9.99
Delivery by Thu, May 01
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Urban Factory CYCLEE Eco-Designed Ambidextrous Computer Mouse, Black (GWM01UF)~#|#~sp230589293_sc7Urban Factory CYCLEE Eco-Designed Ambidextrous Computer Mouse, Black (GWM01UF)~#|#~sp233836674_sc7
Item: 24589140
Model: UBFGWM01UF
No reviews yet
Price is $20.99
Delivery by Thu, May 01
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Logitech MX Vertical Wireless Ergonomic Ambidextrous Optical Mouse, Graphite (910-005447)~#|#~sp30223802_sc7Logitech MX Vertical Wireless Ergonomic Ambidextrous Optical Mouse, Graphite (910-005447)~#|#~sp30223851_sc7
Item: IM15GG879
Model: 910-005447
Price is $130.56
Free delivery by Thu, Apr 24
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SteelSeries AEROX 3 Ergonomic Optical USB Gaming Mouse, Onyx (62611)~#|#~C2D1B1BE-137A-4E60-A6C851B260E03AE5_sc7
Item: IM100GF04
Model: 62611
No reviews yet
Price is $62.39
Free delivery by Thu, Apr 24
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Adesso iMouse V30 Wireless Ergonomic Vertical Optical Mouse, Black~#|#~sp246475070_sc7Adesso iMouse V30 Wireless Ergonomic Vertical Optical Mouse, Black~#|#~sp246475069_sc7
Item: 24602989
Model: IMOUSE V30
No reviews yet
Price is $71.59
Free delivery 
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Logitech Lift for Business Wireless Ergonomic Vertical Left Handed Optical USB Mouse, Graphite (910-006492)~#|#~FFBAFDBE-E401-4BFA-9CCAB08A477F74A2_sc7Logitech Lift for Business Wireless Ergonomic Vertical Left Handed Optical USB Mouse, Graphite (910-006492)~#|#~3B1788A1-0E7B-423B-8F3359C1FE8AACF1_sc7
Item: IM100HA61
Model: 910-006492
No reviews yet
Price is $73.99
Free delivery by Thu, Apr 24
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Logitech Lift for Business Wireless Ergonomic Vertical Optical Bluetooth & USB Mouse, Off-White (910-006469)~#|#~74C4B1B9-8684-463A-BCFABAA8FC7E38E1_sc7Logitech Lift for Business Wireless Ergonomic Vertical Optical Bluetooth & USB Mouse, Off-White (910-006469)~#|#~D3275A07-45E8-42EB-A3D7DB9BD72B4EEE_sc7
Item: 24531607
Model: 910-006469
Price is $76.99
Free delivery by Thu, Apr 24
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Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Space Gray (910-006569)~#|#~9A3818CE-9B00-4D0B-9D161A362EBD5AEB_sc7Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Space Gray (910-006569)~#|#~68DFC64F-737E-4B6F-9824DA9FF3EB0541_sc7
Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Space Gray (910-006569) is In-store only
Item: 24532679
Model: 910-006569
Price is $99.99
1-hr pickup
Razer Basilisk X HyperSpeed Wireless Ergonomic Optical Gaming Mouse, Black (5809509)~#|#~sp102300223_sc7Razer Basilisk X HyperSpeed Wireless Ergonomic Optical Gaming Mouse, Black (5809509)~#|#~sp102300458_sc7
Razer Basilisk X HyperSpeed Wireless Ergonomic Optical Gaming Mouse, Black (5809509) is In-store only
Item: 24438340
Model: 5809509
Price is $69.99
1-hr pickup
Logitech Signature M650 L Wireless Ergonomic Optical Mouse, Graphite (910-006231)~#|#~C07C535C-723F-4C87-934DE7005B4F2E7F_sc7Logitech Signature M650 L Wireless Ergonomic Optical Mouse, Graphite (910-006231)~#|#~9F2A8376-DD91-4E0C-883FD6F510F0AD9A_sc7
Logitech Signature M650 L Wireless Ergonomic Optical Mouse, Graphite (910-006231) is In-store only
Item: 24516906
Model: 910-006231
Price is $43.99
1-hr pickup
Delton Ergonomic 12 Ergonomic Vertical Optical USB Gaming Mouse, Black (DMERG12-U)~#|#~3B69A002-647C-4B35-91E5CB230CB2D389_sc7Delton Ergonomic 12 Ergonomic Vertical Optical USB Gaming Mouse, Black (DMERG12-U)~#|#~0A2237F6-26FF-41C6-B49E3A37AB20FB3D_sc7
Item: 24553379
Model: DMERG12-U
Price is $26.89
Delivery by Fri, Apr 25
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Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Sheer Dream (910-007283)~#|#~F6405455-ECC2-4EE7-B5D5FD8947EAD13B_sc7Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Sheer Dream (910-007283)~#|#~98D3CE9A-069B-4571-8CDA81E2D50D2667_sc7
Logitech M340 Wireless Ergonomic Ambidextrous Optical USB Mouse, Sheer Dream (910-007283) is Out of stock
Item: IM1KS0742
Model: 910-007283
No reviews yet
Price is $22.99
Logitech Lift for Business Wireless Ergonomic Vertical Optical USB Mouse, Graphite (910-006491)~#|#~1950F1DB-4DEB-4DA4-884DC70DAF3F8886_sc7Logitech Lift for Business Wireless Ergonomic Vertical Optical USB Mouse, Graphite (910-006491)~#|#~648B5F3E-33F1-408D-AF47BD38ED6C1D14_sc7
Logitech Lift for Business Wireless Ergonomic Vertical Optical Mouse, Graphite (910-006491) is Out of stock
Item: IM100HA60
Model: 910-006491
Price is $69.99
Kensington MY230 EQ Wireless Ergonomic Ambidextrous Optical USB Mouse, Black (K75303NA~#|#~FFB67924-C08D-492B-93DC0CDC238130F0_sc7Kensington MY230 EQ Wireless Ergonomic Ambidextrous Optical USB Mouse, Black (K75303NA~#|#~DD62E4B4-5BA7-4F83-BF958A129804A67D_sc7
Kensington MY230 EQ Wireless Ergonomic Ambidextrous Optical USB Mouse, Black (K75303NA is Out of stock
Item: IM1S66022
Model: K75303NA
No reviews yet
Price is $39.99
Logitech G Wireless Ergonomic Optical USB Type A Gaming Mouse, White (910-007205)~#|#~B6BEB176-A9C8-459C-8AAD8EDD46E6C8BD_sc7Logitech G Wireless Ergonomic Optical USB Type A Gaming Mouse, White (910-007205)~#|#~77FB7609-82A7-49FD-B1BAA63F50C444D1_sc7
Logitech G Wireless Ergonomic Optical USB Type A Gaming Mouse, White (910-007205) is Out of stock
Item: IM1NJ6791
Model: 910-007205
No reviews yet
Price is $94.54
HP 150 Wireless Ergonomic Optical Mouse, Black (2S9L1AA)~#|#~AF3FAD2C-1BDE-4E39-BB3E607D020C3850_sc7HP 150 Wireless Ergonomic Optical Mouse, Black (2S9L1AA)~#|#~1D9F3D87-4C05-4C6E-8C4767970F35FA74_sc7
HP 150 Wireless Ergonomic Optical Mouse, Black (2S9L1AA) is Out of stock
Item: 24577035
Model: 2S9L1AA
No reviews yet
Price is $21.09
Logitech Pro X Superlight 2 Dex Wireless Ergonomic Optical Gaming Mouse, Pink (910-007371)~#|#~CB89C04F-DF33-4DC8-B704791BB668C067_sc7Logitech Pro X Superlight 2 Dex Wireless Ergonomic Optical Gaming Mouse, Pink (910-007371)~#|#~B10E7A9A-D425-4DAD-BF499389352408B4_sc7
Logitech Pro X Superlight 2 Dex Wireless Ergonomic Optical Gaming Mouse, Pink (910-007371) is Out of stock
Item: IM1NP4554
Model: 910-007371
No reviews yet
Cherry AK-PMH3 Medical Wireless Ergonomic Ambidextrous Optical USB Mouse, White (AK-PMH3OS-FUS-W)~#|#~EE577AD7-3BDA-45FF-A43EF8F2A7F169A2_sc7Cherry AK-PMH3 Medical Wireless Ergonomic Ambidextrous Optical USB Mouse, White (AK-PMH3OS-FUS-W)~#|#~B7F075EF-7BC3-4036-AFC71D7198832400_sc7
Cherry AK-PMH3 Medical Wireless Ergonomic Ambidextrous Optical USB Mouse, White (AK-PMH3OS-FUS-W) is Out of stock
Item: 24624373
Model: AK-PMH3OS-FUS-W
No reviews yet
Price is $79.00
Adesso iMouse T40 Wireless Ergonomic Ambidextrous Optical Mouse, Red/Black~#|#~m007167965_sc7
Adesso iMouse T40 Wireless Ergonomic Ambidextrous Optical Mouse, Red/Black is Out of stock
Item: IM15KA517
Model: IMOUSE T40
Price is $58.31
Logitech M720 Triathlon Wireless Ergonomic Optical USB Mouse, Black (910-004790)~#|#~2FCF84F7-6BF6-49DD-884646AF26B66A78_sc7Logitech M720 Triathlon Wireless Ergonomic Optical USB Mouse, Black (910-004790)~#|#~EC8E5FDE-316B-4169-8882166C96B57E3A_sc7
Logitech M720 Triathlon Wireless Ergonomic Optical Bluetooth & USB Mouse, Black (910-004790) is Out of stock
Item: IM14T7943
Model: 910-004790
Price is $49.14
Logitech M196 Wireless Ergonomic Ambidextrous Optical Mouse, Gray (910-007437)~#|#~C6D7BD76-FDF4-4163-ACFE0ECBAF1AA537_sc7
Logitech M196 Wireless Ergonomic Ambidextrous Optical Mouse, Gray (910-007437) is Out of stock
Item: IM1NP4571
Model: 910-007437
No reviews yet
Price is $18.88
Logitech Signature M650 L Wireless Ergonomic Optical USB Mouse, Classic Blue (910-006232)~#|#~sp170355468_sc7Logitech Signature M650 L Wireless Ergonomic Optical USB Mouse, Classic Blue (910-006232)~#|#~CF8A0FB4-D4CE-48BB-AC7E56C0BF80F8AF_sc7
Logitech Signature M650 L Wireless Ergonomic Optical USB Mouse, Classic Blue (910-006232) is Out of stock
Item: IM19VP961
Model: 910-006232
Price is $43.99
Adesso iMouse V10 Wireless Ergonomic Optical Mouse, Black~#|#~217414CF-CA09-4DA8-907369E4475B4215_sc7Adesso iMouse V10 Wireless Ergonomic Optical Mouse, Black~#|#~DB05FF65-9591-42B7-B11745ED1D557828_sc7
Adesso iMouse V10 Wireless Ergonomic Optical Mouse, Black is Out of stock
Item: 24542349
Model: IMOUSE V10
No reviews yet
Price is $42.79
SteelSeries Rival 5 Ergonomic Optical USB Gaming Mouse, Matte Black (62551)~#|#~sp138469363_sc7SteelSeries Rival 5 Ergonomic Optical USB Gaming Mouse, Matte Black (62551)~#|#~sp138469353_sc7
SteelSeries Rival 5 Ergonomic Optical USB Gaming Mouse, Matte Black (62551) is Out of stock
Item: IM19DB974
Model: 62551
No reviews yet
Price is $59.99
Kensington Mouse for Life Ergonomic Ambidextrous Optical USB Mouse, Black (K74531WW)~#|#~m004074525_sc7Kensington Mouse for Life Ergonomic Ambidextrous Optical USB Mouse, Black (K74531WW)~#|#~m003758662_sc7
Kensington Mouse for Life Ergonomic Ambidextrous Optical USB Mouse, Black (K74531WW) is Out of stock
Item: IM13B6721
Model: K74531WW
Price is $21.49
Samsung Slim Wireless Ergonomic Mouse, Black (EJ-M3400DBEGUS)~#|#~sp171725000_sc7
Samsung Slim Wireless Ergonomic Mouse, Black (EJ-M3400DBEGUS) is Out of stock
Item: IM105BH25
Model: EJ-M3400DBEGUS
Price is $42.26
Logitech ERGO M575 Wireless Ergonomic Trackball Mouse, Off White (910-006437)~#|#~sp152694912_sc7Logitech ERGO M575 Wireless Ergonomic Trackball Mouse, Off White (910-006437)~#|#~895586B8-89B2-4977-BFCDB0EAA8062C2B_sc7
Logitech ERGO M575 Wireless Ergonomic Trackball Mouse, Off White (910-006437) is Out of stock
Item: 24507798
Model: 910-006437
No reviews yet
Price is $54.99
Logitech MX Anywhere 3 for Mac Wireless Ergonomic Laser USB Mouse, Pale Gray (910-005899)~#|#~B758F92F-D01F-4AAD-ADA6A459288A4F63_sc7Logitech MX Anywhere 3 for Mac Wireless Ergonomic Laser USB Mouse, Pale Gray (910-005899)~#|#~2B7BF126-813E-45BB-95324BFB7BCCE89B_sc7
Logitech MX Anywhere 3 for Mac Wireless Ergonomic Laser USB Mouse, Pale Gray (910-005899) is Out of stock
Item: IM18GY417
Model: 910-005899
No reviews yet
Price is $93.03

Trending now

Anyone who spends a lot of time on a computer can benefit from using an ergonomic mouse. These innovative devices allow the hand to rest in a healthy position, reducing strain and preventing repetitive stress injuries so users can work or play all day comfortably.

Today's computer users have a wide selection of styles to choose from. Wireless and compact designs deliver healthy posture without tangled cords. Ambidextrous models are comfortable for right or left handed use, and alternative devices accommodate users who use their fingers, palms or a stylus to control the pointer.

Comfortable Hand Position for Hours of Work or Play

There are a variety of shapes and sizes of ergonomic mice to choose from including vertical, handshoe and fingertip. Vertical designs allow users to navigate with their arm instead of the wrist reducing wrist pressure that is associated with carpal tunnel syndrome. Handshoe shaped mice are contoured to form-fit the hand, so fingers rest comfortably when not in use and clicking requires minimal motion. Fingertip models require no wrist or arm movement. Instead, they are controlled using quick finger movements in much the same way as writing.

Wireless Ergonomic Mice Offer Freedom of Movement

Wireless mice are a good choice for users who have small working spaces or who travel a lot. They are connected to the computer using Bluetooth or a USB dongle instead of a cord. Wireless designs are also convenient for conference room systems, classrooms and media centers, where users are standing or sitting a significant distance from the computer.

Choose Ambidextrous Models for Left Hand or Right Hand Use

Ambidextrous mice are comfortable for both right handed and left handed use. They are popular with gamers who like to switch hands and artists who illustrate with either hand. Ambidextrous styles are also a good choice for public terminals and shared workspaces such as conference rooms, touchdown spaces and co-op offices.

Compact Designs Fit Easily in Small Bags

For productivity on the go, choose compact devices that travel well. Handshoe shaped mice are flat and stow easily in backpacks and luggage. For an even smaller ergonomic mouse, choose a fingertip model. These small designs deliver healthy hand and wrist posture without the bulky design.

Alternative Designs Deliver a Range of Benefits

Alternative ergonomic mice offer function without the traditional mouse shape. Common alternative designs include touchpads, central pointing devices and trackballs. Touchpads and tablets allow users to navigate, draw and click with the touch of their fingers or with a stylus. Trackballs are popular among gamers, drafters, animators and engineers. They feature fast and precise cursor and pointer movement since users roll the ball instead of moving the entire mouse.

To find the best ergonomic mouse, consider the needs of the user. For busy professionals and students who need mobility and freedom of movement, look for wireless and compact designs. Most models come in left handed or right handed versions and ambidextrous models are a good choice for shared terminals and public computers. Alternative models are ideal for specialized users such as illustrators and engineers or for users who require special accommodations.