Sponsored Products
Logitech M720 Triathlon Wireless Ergonomic Optical Mouse, Black (910-004790)~#|#~5AB2B329-41CF-4292-82755E6648820B87_sc7
Logitech M720 Triathlon Wireless Ergonomic Optical Mouse, Black (910-004790)~#|#~6E855D99-65BD-490D-A9014F8319AB3455_sc7
Item # : 2392528
Model # : 910-004790
  • Wireless, multi-device mouse for convenience
  • Bluetooth and USB connectivity offers flexibility
Price is $44.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Logitech ERGO M575S Wireless Ergonomic Trackball Mouse, Black (910-007026)~#|#~B4DD0A46-DA1C-452F-BBECF8A1E1756542_sc7
Logitech ERGO M575S Wireless Ergonomic Trackball Mouse, Black (910-007026)~#|#~0ABE2215-0FC3-48BB-8464878C7D572072_sc7
Item # : 24460735
Model # : 910-007026
WORK IN YOUR COMFORT ZONE
  • You may receive either the M575 S or the previous M575 model (part number 910-006197) while inventory remains.
  • 25% less muscle strain in your forearm: This wireless ergonomic mouse has been developed with Logi Ergo Lab experts, user-tested and certified by ergonomists for all-day comfort
Price is $49.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Logitech MX Ergo S Plus Wireless Ergonomic Trackball Mouse, Black (910-007247)~#|#~303BA12E-557C-4C33-8FFF4F96ADB232E8_sc7
Logitech MX Ergo S Plus Wireless Ergonomic Trackball Mouse, Black (910-007247)~#|#~4C5850A5-6D45-4770-ABAEEB79F317316B_sc7
Item # : 2764655
Model # : 910-007247
Elevate your comfort and precision
  • You may receive either the MX Ergo S Plus or the previous MX Ergo Plus model (part number 910-005178) while inventory remains.
  • Advanced thumb control: The MX Ergo S Plus wireless trackball mouse gives more control with less movement; switch between speed and high-precision tracking at the tap of a button
Price is $119.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Logitech M705 Marathon Wireless Ergonomic Optical USB Mouse, Charcoal (910-001935)~#|#~141FEADB-0A7D-4458-8914F05C3E840A23_sc7
Logitech M705 Marathon Wireless Ergonomic Optical USB Mouse, Charcoal (910-001935)~#|#~692CE431-845C-41E0-B4139CE75D185072_sc7
Item # : 870571
Model # : 910-001935
The precision mouse that’s built for the long haul, with a sculpted shape, dual-mode scrolling, and more control so you can tackle any task.
  • 3-Year Battery Life: This wireless optical mouse features an auto-sleep power-saving mode and on/off switch so you can enjoy up to 3 years (1) of charge on 2 AA batteries
  • Designed for Comfort: Sculpted with comfort in mind, your wireless computer mouse follows the natural curve of your right hand, and all controls are within your reach
Price is $39.99
Free Next-Day eligible by tomorrow
1-hr pickup
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Staples TECH Wireless Ergonomic Curved Optical USB Mouse, Black (ST62599)~#|#~E21489FD-F764-4C90-92C265E7B1FE3B28_sc7
Staples TECH Wireless Ergonomic Curved Optical USB Mouse, Black (ST62599)~#|#~0C0DB036-3504-4B04-89726D10A306DEBB_sc7
Item # : 24596651
Model # : ST62599
The Staples TECH Wireless Optical Ergonomic Mouse gives you comfort and performance
  • Ergonomic design to minimize discomfort
  • Made to fit most hand sizes
Price is $16.39
Next-Day Delivery by tomorrow
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Delton Ergonomic 12 Wireless Ergonomic Vertical Optical Gaming Mouse, Black (DMERG12-WB)~#|#~D03FAC66-AB29-4C98-91526B4C54A88B53_sc7
Delton Ergonomic 12 Wireless Ergonomic Vertical Optical Gaming Mouse, Black (DMERG12-WB)~#|#~37C456D2-5F15-46CC-A228ADBD9186B3FD_sc7
Item # : 24553378
Model # : DMERG12-WB
Reduce wrist strain and stay comfortable throughout your work day on nearly any surface with this Delton wireless ergonomic mouse.
  • Superior CMOS sensors make this optical mouse perfect for everyday use at home, in the office, or on the go
  • Works within a wireless range of up to 30' with the included 2.4GHz USB dongle
Price is $34.39
Delivery by Fri, Jul 18
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Delton S10 Wireless Ergonomic Curved Optical Mouse, Black (DMERGS10-WB)~#|#~F776B5C7-36B4-4BA9-B385143D7A70F97F_sc7
Delton S10 Wireless Ergonomic Curved Optical Mouse, Black (DMERGS10-WB)~#|#~6E88FAEE-8A3F-48BF-BE95B16E77F27703_sc7
Item # : 24580934
Model # : DMERGS10-WB
No reviews yet
  • Advanced CMOS sensors make this optical mouse perfect for everyday use at home, in the office, or on the go
  • Ultrafast 2.4Ghz wireless technology delivers superfast response time, ensuring accuracy and precision
Price is $40.99
Free delivery by Fri, Jul 18
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Delton Ergonomic 12 Ergonomic Vertical Optical USB Gaming Mouse, Black (DMERG12-U)~#|#~3B69A002-647C-4B35-91E5CB230CB2D389_sc7
Delton Ergonomic 12 Ergonomic Vertical Optical USB Gaming Mouse, Black (DMERG12-U)~#|#~0A2237F6-26FF-41C6-B49E3A37AB20FB3D_sc7
Item # : 24553379
Model # : DMERG12-U
  • Superior CMOS sensors make this optical mouse perfect for everyday use at home, in the office, or on the go
  • Work comfortably at your desk or just about anywhere: just plug the 5' USB cable into any PC, laptop or tablet, and you're ready to go
Price is $28.49
Delivery by Fri, Jul 18
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Razer Basilisk V3 Ergonomic Optical USB Gaming Mouse, Black (RZ0104000100R3)~#|#~75692D19-8D1B-440E-BE4F2862EB848292_sc7
Razer Basilisk V3 Ergonomic Optical USB Gaming Mouse, Black (RZ0104000100R3)~#|#~4284EF50-DC3B-4817-B745D62612DDB21B_sc7
Item # : 24536636
Model # : RZ0104000100R3
  • Fast and precise optical gaming mouse for everyday use at home or in the office
  • Wired connectivity for accuracy and dependability
Price is $69.99
Free delivery by Thu, Jul 24
1-hr pickup
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Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020)~#|#~D108F7C1-397B-4F02-9E503C29F5279CD0_sc7
Logitech G305 Lightspeed Wireless Ergonomic Optical Gaming Mouse, Lilac (910-006020)~#|#~9602D753-EE7F-4345-B5265DBB441A1C2F_sc7
Item # : 24489781
Model # : 910-006020
Travel Mouse - Optical - Wireless - Radio Frequency - 2.40 GHz - Lilac - 12000 dpi - 6 Button(s)
  • HERO Sensor - Next-generation HERO sensor delivers incredible performance and up to 10x the power efficiency over previous generations. HERO is an optical sensor capable of exceptional accuracy and responsiveness with 400 IPS precision and up to 12,000 DPI sensitivity.
  • LIGHTSPEED Wireless - Ultra-fast LIGHTSPEED Wireless technology gives you a lag-free gaming experience. G305 delivers incredible responsiveness and reliability with a super fast 1 ms report rate for competition-level performance.
Price is $59.99
Free delivery by Fri, Jul 18
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Logitech Signature M650 L Wireless Ergonomic Left Handed Optical Mouse, Graphite (910-006234)~#|#~2FE85650-C31F-4DEC-8F5EAB92029AA355_sc7
Logitech Signature M650 L Wireless Ergonomic Left Handed Optical Mouse, Graphite (910-006234)~#|#~945228AD-F884-4579-B2377B7095A97013_sc7
Item # : 24516903
Model # : 910-006234
SCROLLS SMARTER. FITS BETTER.
  • Scroll smarter: With Logitech Signature M650 Wireless Mouse you get line-by-line precision for documents and super-fast scrolling for long web pages; simply switch modes with a flick of the SmartWheel
  • Left handed design: This comfortable full size mouse is designed for larger hands, for the optimal fit for left handed users
Price is $39.99
Free delivery by Fri, Jul 18
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Contour Design RollerMouse Pro3 Ergonomic Ambidextrous Rollerbar USB Mouse, Black (RM-PRO3)~#|#~sp37727950_sc7
Contour Design RollerMouse Pro3 Ergonomic Ambidextrous Rollerbar USB Mouse, Black (RM-PRO3)~#|#~sp37727954_sc7
Item # : 2756654
Model # : RM-PRO3
Find a new way to interact with your computer with this Contour Design RollerMouse Pro3 mouse alternative.
  • Wired connectivity for accuracy and dependability
  • Rollerbar mouse for improved precision
Price is $279.00
Free delivery 
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Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Pale Gray (910-006570)~#|#~A9283F17-9F18-43BE-B4542F3E4D83BC18_sc7
Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Pale Gray (910-006570)~#|#~CEF56B21-D442-4D40-9ACCA86DAC186771_sc7
Logitech MX Master 3S for Mac Wireless Ergonomic Optical Mouse, Pale Gray (910-006570) is In-store only
Item # : 24532676
Model # : 910-006570
  • Optical mouse perfect for everyday use at home or in the office
  • Take this reliable wireless mouse anywhere with 32.81' wireless operating distance
Price is $119.99
Logitech Lift for Business Wireless Ergonomic Vertical Optical Bluetooth & USB Mouse, Off-White (910-006469)~#|#~74C4B1B9-8684-463A-BCFABAA8FC7E38E1_sc7
Logitech Lift for Business Wireless Ergonomic Vertical Optical Bluetooth & USB Mouse, Off-White (910-006469)~#|#~D3275A07-45E8-42EB-A3D7DB9BD72B4EEE_sc7
Item # : 24531607
Model # : 910-006469
  • This Bluetooth mouse supports a clutter-free workplace
  • Take this reliable wireless mouse anywhere
Price is $79.99
Free delivery by Fri, Jul 18
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Delton S22 Wireless Ergonomic Vertical Optical Mouse, Gray/Black (DMERGS22-WB)~#|#~ABD12782-D125-4548-98943E021B04FA01_sc7
Delton S22 Wireless Ergonomic Vertical Optical Mouse, Gray/Black (DMERGS22-WB)~#|#~944E7227-1A55-4F3B-9A9546B078614C42_sc7
Item # : 24586504
Model # : DMERGS22-WB
No reviews yet
Elevate your comfort and eliminate wrist pain with the Delton S22 vertical-grip ergonomic wireless mouse. The S22 features a rheumatologist-recommended wrist-friendly design, silent operation, 2.4 GHz wireless connectivity, a 30-foot range, easy auto-pair setup, multi-DPI settings, and universal OS compatibility.
  • This optical mouse is specially shaped to reduce strain on the wrist and hand, promoting a more natural and comfortable position for long-term use
  • Offers a reliable 2.4GHz wireless connection that reduces cable clutter on your desk
Price is $48.99
Free delivery by Fri, Jul 18
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Logitech MX Ergo Plus Wireless Ergonomic Optical Mouse, Black (910-005178)~#|#~sp162863831_sc7
Logitech MX Ergo Plus Wireless Ergonomic Optical Mouse, Black (910-005178)~#|#~sp162863889_sc7
Item # : IM16YE866
Model # : 910-005178
The Logitech MX Ergo Plus advanced wireless trackball mouse reduces muscle strain compared to a regular mouse.
  • MX Ergo Advanced Wireless Trackball Mouse
  • Smart adjustable hinge plus extra 10° wedge for customized hand position and greater comfort. Choose the best angle for you 0°, 20° or 30°.
Price is $119.99
Free delivery by Fri, Jul 18
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Logitech G305 Lightspeed Wireless Optical Gaming Mouse, White (910-005289)~#|#~4F8A4AA5-2C5C-4926-9D67CE666CB842C8_sc7
Logitech G305 Lightspeed Wireless Optical Gaming Mouse, White (910-005289)~#|#~6C2697DC-2256-4433-A2345DCC1542F57D_sc7
Item # : 24489805
Model # : 910-005289
Logitech G305 - Mouse - optical - 6 buttons - wireless - LIGHTSPEED - USB wireless receiver - white
  • HERO Sensor - Next-generation HERO sensor delivers incredible performance and up to 10x the power efficiency over previous generations. HERO is an optical sensor capable of exceptional accuracy and responsiveness with 400 IPS precision and up to 12,000 DPI sensitivity.
  • LIGHTSPEED Wireless - Ultra-fast LIGHTSPEED Wireless technology gives you a lag-free gaming experience. G305 delivers incredible responsiveness and reliability with a super fast 1 ms report rate for competition-level performance.
Price is $59.99
Free delivery by Fri, Jul 18
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Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)~#|#~sp147267338_sc7
Logitech G203 LIGHTSYNC Ergonomic Optical USB Gaming Mouse, Black (910-005790)~#|#~4CA76A13-9D01-4413-A5EA6675CE2580A0_sc7
Item # : 24450019
Model # : 910-005790
Make the most of your game time with G203 gaming mouse, featuring LIGHTSYNC technology, a gaming-grade sensor and a classic 6-button design. Light up your game … and your desk.
  • Choose from vibrant animations, game- and media-driven settings, or program your own from approximately 16.8 million colors.
  • Pick one color, blend three, choose a fun animation preset, or make your own. The choice is yours! You can even sync your mouse with other Logitech G LIGHTSYNC gear so it’s a perfect match.
Price is $34.99
Delivery by Mon, Jul 21
1-hr pickup
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Humanscale Pro-Click Wireless Ergonomic Optical Mouse, White (PROCLICK-NA)~#|#~C361D43A-6A0B-4F36-B772DC4C7295B8C7_sc7
Humanscale Pro-Click Wireless Ergonomic Optical Mouse, White (PROCLICK-NA)~#|#~604F268B-27E7-46F5-A1D63DF105A693DC_sc7
Item # : 24603517
Model # : PROCLICK-NA
No reviews yet
Pro Click, designed in collaboration with Razer ™, is a state-of-the-art wireless ergonomic computer mouse built for comfort and productivity. Engineered by top ergonomists and designers, Pro Click’s shape contours to the user’s palm, eliminating any contact between the hand and the work surface. Designed with a 30-degree tilt, Pro Click promotes a natural ergonomic arm posture to alleviate unwanted wrist strain for all-day comfort.
  • Pro Click’s Razer 5G Advanced Optical Sensor ensures that every movement is tracked for unrivaled precision. The 16,000 DPI sensor accounts for even the slightest of movements, offering day-long comfort by reducing the amount of wrist movement needed to move the cursor.
  • Designed as the ultimate ergonomic wireless for productivity, the Razer Pro Click is durable for up to 50 million clicks, while its extended battery powers up to 400 hours of use.
Price is $169.00
Free delivery 
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Kensington Pro Fit Wireless Ergonomic Vertical Optical Mouse, Gray (K75520WW)~#|#~sp104402113_sc7
Kensington Pro Fit Wireless Ergonomic Vertical Optical Mouse, Gray (K75520WW)~#|#~sp104402112_sc7
Item # : IM16LQ261
Model # : K75520WW
  • This 2.4GHz mouse supports a clutter-free workplace
  • Take this reliable wireless mouse anywhere
Price is $50.14
Free delivery by Tue, Jul 22
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Delton S18 Wireless Ergonomic Optical Mouse, Black (DMS18-WB)~#|#~F43CE980-EF6D-4F29-AADC8ED24816ECDA_sc7
Delton S18 Wireless Ergonomic Optical Mouse, Black (DMS18-WB)~#|#~D76E8252-FFB7-4EF3-A34757D0A9D032C3_sc7
Item # : 24571655
Model # : DMS18-WB
  • Precise CMOS sensor makes this optical mouse perfect for everyday use at home, in the office, or on the go
  • Ultrafast 2.4GHz wireless technology delivers 1ms response time, ensuring accuracy and precision
Price is $71.49
Free delivery by Fri, Jul 18
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Logitech G305 Lightspeed Wireless Optical Gaming Mouse, Blue (910-006012)~#|#~92D9EF32-5FE4-4EA5-A5AE28127F445104_sc7
Logitech G305 Lightspeed Wireless Optical Gaming Mouse, Blue (910-006012)~#|#~A4671C1A-28DD-423B-90E7C59332F99FD3_sc7
Item # : 24489810
Model # : 910-006012
Travel Mouse - Optical - Wireless - Radio Frequency - 2.40 GHz - Blue - 12000 dpi - 6 Button(s)
  • HERO Sensor - Next-generation HERO sensor delivers incredible performance and up to 10x the power efficiency over previous generations. HERO is an optical sensor capable of exceptional accuracy and responsiveness with 400 IPS precision and up to 12,000 DPI sensitivity.
  • LIGHTSPEED Wireless - Ultra-fast LIGHTSPEED Wireless technology gives you a lag-free gaming experience. G305 delivers incredible responsiveness and reliability with a super fast 1 ms report rate for competition-level performance.
Price is $59.99
Free delivery by Tue, Jul 22
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Adesso iMouse G2 Ergonomic Ambidextrous Optical USB Mouse, Black~#|#~m006851930_sc7
Item # : IM19L0562
Model # : IMOUSE G2
  • Plug and play USB interface for a quick and perfect configuration
  • Optical LED for smoother movement and hassle-free performance
Price is $24.00
Delivery by Fri, Jul 18
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Urban Factory BIG CRAZY Ergonomic Ambidextrous Optical USB Mouse, Black (UBFBCM01UF)~#|#~sp179263779_sc7
Urban Factory BIG CRAZY Ergonomic Ambidextrous Optical USB Mouse, Black (UBFBCM01UF)~#|#~sp179263774_sc7
Item # : 24539493
Model # : UBFBCM01UF
No reviews yet
  • Black matte wired USB 2.0 mouse
  • 3-button mouse for the right- and left-handed (ambidextrous)
Price is $9.99
Delivery by Thu, Jul 24
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Trending now

Anyone who spends a lot of time on a computer can benefit from using an ergonomic mouse. These innovative devices allow the hand to rest in a healthy position, reducing strain and preventing repetitive stress injuries so users can work or play all day comfortably.

Today's computer users have a wide selection of styles to choose from. Wireless and compact designs deliver healthy posture without tangled cords. Ambidextrous models are comfortable for right or left handed use, and alternative devices accommodate users who use their fingers, palms or a stylus to control the pointer.

Comfortable Hand Position for Hours of Work or Play

There are a variety of shapes and sizes of ergonomic mice to choose from including vertical, handshoe and fingertip. Vertical designs allow users to navigate with their arm instead of the wrist reducing wrist pressure that is associated with carpal tunnel syndrome. Handshoe shaped mice are contoured to form-fit the hand, so fingers rest comfortably when not in use and clicking requires minimal motion. Fingertip models require no wrist or arm movement. Instead, they are controlled using quick finger movements in much the same way as writing.

Wireless Ergonomic Mice Offer Freedom of Movement

Wireless mice are a good choice for users who have small working spaces or who travel a lot. They are connected to the computer using Bluetooth or a USB dongle instead of a cord. Wireless designs are also convenient for conference room systems, classrooms and media centers, where users are standing or sitting a significant distance from the computer.

Choose Ambidextrous Models for Left Hand or Right Hand Use

Ambidextrous mice are comfortable for both right handed and left handed use. They are popular with gamers who like to switch hands and artists who illustrate with either hand. Ambidextrous styles are also a good choice for public terminals and shared workspaces such as conference rooms, touchdown spaces and co-op offices.

Compact Designs Fit Easily in Small Bags

For productivity on the go, choose compact devices that travel well. Handshoe shaped mice are flat and stow easily in backpacks and luggage. For an even smaller ergonomic mouse, choose a fingertip model. These small designs deliver healthy hand and wrist posture without the bulky design.

Alternative Designs Deliver a Range of Benefits

Alternative ergonomic mice offer function without the traditional mouse shape. Common alternative designs include touchpads, central pointing devices and trackballs. Touchpads and tablets allow users to navigate, draw and click with the touch of their fingers or with a stylus. Trackballs are popular among gamers, drafters, animators and engineers. They feature fast and precise cursor and pointer movement since users roll the ball instead of moving the entire mouse.

To find the best ergonomic mouse, consider the needs of the user. For busy professionals and students who need mobility and freedom of movement, look for wireless and compact designs. Most models come in left handed or right handed versions and ambidextrous models are a good choice for shared terminals and public computers. Alternative models are ideal for specialized users such as illustrators and engineers or for users who require special accommodations.