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Kleenex Standard Facial Tissue, 2-Ply, 144 Sheets/Box, 3 Boxes/Pack (37392)Kleenex Standard Facial Tissue, 2-Ply, 144 Sheets/Box, 3 Boxes/Pack (37392)
16% off
4.99
Item #56014
Model #50219/37392
  • Standard facial tissues are soft and gentle on the skin but tough on messes
  • 2-ply thickness offers outstanding quality and softness
$4.99
Reg.  $5.99
3/Pack
Free delivery
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Kleenex Antiviral Facial Tissue, 3-Ply, 60 Sheets/Box, 12/Carton (21286CT)
38.49
Item #1912986
Model #21286CT
  • Antiviral facial tissue can help stop the spread of germs, 99.9% of cold, and flu viruses
  • 3-ply construction provides superior strength and durability
$38.49
12/Carton
Free delivery
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Kleenex Boutique Standard Facial Tissues, 2-Ply, 95 Sheets/Box, 6/Pack (21271)
13.19
Item #826830
Model #21271
  • Standard facial tissues are soft and gentle on the skin but tough on messes
  • 2-ply thickness offers outstanding quality and softness
$13.19
6/Pack
Free delivery
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Puffs Plus Lotion Facial Tissues, 2-Ply, 56 Sheets/Box, 4 Boxes/Pack (34899)
6.59
Item #1917288
Model #34899
  • Lotion tissues help soothe irritated noses by locking in moisture better than regular tissues
  • 2-ply thickness offers outstanding quality and softness
$6.59
4/Pack
Free delivery
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Staples Facial Tissue, 2-Ply, White, Flat Box, 160 Sheets/Box, 4 Boxes/Pack (53224)Staples Facial Tissue, 2-Ply, White, Flat Box, 160 Sheets/Box, 4 Boxes/Pack (53224)
4.69
Item #24322419
Model #53224
  • 2-Ply Facial Tissue
  • Strong and Absorbent
$4.69
4/Pack
Free delivery
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Kleenex Standard Facial Tissue, 2-Ply, White, 125 Sheets/Box, 12 Boxes/Pack (03076)Kleenex Standard Facial Tissue, 2-Ply, White, 125 Sheets/Box, 12 Boxes/Pack (03076)
21.49
Item #470745
Model #03076
  • Standard facial tissues are soft and gentle on the skin but tough on messes
  • 2-ply thickness offers outstanding quality and softness
$21.49
12/Carton
Free delivery
Add to cart
Puffs® Facial Tissues, 2-Ply
4.99
Item #SS993940
  • 2-ply, white tissues
  • Color and perfume free
Multiple options
As low as  $4.99
3/Pack
Free delivery
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Kleenex Boutique Standard Facial Tissue, 2-Ply, 95 Sheets/Box, 36 Boxes/Pack (21270)Kleenex Boutique Standard Facial Tissue, 2-Ply, 95 Sheets/Box, 36 Boxes/Pack (21270)
78.69
Item #915714
Model #21271
  • Standard facial tissues are soft and gentle on the skin but tough on messes
  • 2-ply thickness offers outstanding quality and softness
$78.69
36/Carton
Free delivery
Add to cart
Kleenex Standard Facial Tissue, 2-Ply, White, 100 Sheets/Box, 36 Boxes/Pack (21400CT)Kleenex Standard Facial Tissue, 2-Ply, White, 100 Sheets/Box, 36 Boxes/Pack (21400CT)
57.99
Item #808298
Model #21400CT
  • Standard facial tissues are soft and gentle on the skin but tough on messes
  • 2-ply thickness offers outstanding quality and softness
$57.99
36/Carton
Free delivery
Add to cart
Staples Standard Facial Tissue, 2-Ply, 100 Sheets/Box, 48 Boxes/Pack (21826/33603)Staples Standard Facial Tissue, 2-Ply, 100 Sheets/Box, 48 Boxes/Pack (21826/33603)
40.49
Item #425948
Model #21826/33603
  • Standard facial tissues are soft and gentle on the skin but tough on messes
  • 2-ply thickness offers outstanding quality and softness
$40.49
48/Carton
Free delivery
Add to cart
Keep clean while fighting the cold and flu by having a box of facial tissues ready. Also referred to as paper handkerchiefs, the tissue is made of soft and absorbent sheets used for cleaning the face and nose. This tissue is an essential supply for office desks, bedside tables, hotel rooms, and restrooms. Browse the large inventory of cleaning supplies at Staples to find a wide selection of paper handkerchiefs from leading brands like Kleenex, Puffs, and Perk.

Choose from different types of facial tissues
Manufacturers typically bleach these products to make them white. However, there are also unbleached tissues for those who prefer them. These appear brown and use fewer chemical treatments. Elemental chlorine gas, the bleaching agent commonly used for white paper handkerchiefs, may irritate sensitive skin. Alternatives include elemental chlorine-free (ECF) and processed chlorine-free (PCF) tissues. ECF tissue sheets are not chlorine-free since they use chlorine dioxide, a less harmful chemical, for bleaching. PCF tissues are truly chlorine-free because they use oxygen or hydrogen peroxide as a bleaching agent.

Virgin tissues come from fresh paper pulp, while recycled ones use fibers obtained from paper waste. Virgin paper handkerchiefs are usually softer and more absorbent but recycled ones have lower environmental impact. Other green alternatives for eco-conscious shoppers include tissues sourced from bamboo and sugarcane. Unlike hardwoods, these are fast-growing and easily sustainable plants.

Factors to consider when comparing facial tissues
The ideal paper handkerchief must be soft and strong enough to stand up to nose-blowing, and resist tearing when wet. The ply count is a good indication of tissue softness and strength. Ply refers to the number of layers used in a sheet. These products are available in one to four-ply varieties. One-ply sheets are the thinnest, while two- and three-ply ones are the most common. Generally, tissues with higher ply counts are stronger, softer, and more absorbent than those with lower ones. However, this is not always true, and performance based on ply number varies from one brand to another.

While standard paper handkerchiefs have a plain surface, there are also units with printed and embossed surfaces. These are decorative flourishes with aesthetic appeal. Manufacturers also offer paper handkerchiefs with additives, such as lotions and fragrances. These are softer than regular handkerchiefs and may help moisturize and/or cool the skin. They provide comfort when battling cold and flu during dry winter months by hydrating the skin and reducing redness.

What do the FSC and PEFC Certifications on tissue boxes mean?
The Forest Stewardship Council (FSC) and Program for the Endorsement of Forest Certification (PEFC) certify paper products sourced from sustainably managed forests. There are three types of FSC labels and two types of PEFC labels used on paper handkerchief boxes. PEFC-Certified and PEFC Recycled labels guarantee that the tissues contain at least 70 percent pulp sourced from PEFC-certified forests and recycled sources respectively. FSC 100% indicates that all the wood used in the product comes from an FSC-certified forest. FSC recycled means that the wood used comes from recycled sources with a 15-percent allowance for reused pre-consumer waste. FSC mix guarantees that the product contains at least 70 percent FSC-certified material.

Should you consider hypoallergenic facial tissues?
Hypoallergenic paper handkerchiefs don't contain dyes, perfumes, and other potentially irritating chemical additives commonly used to make these products. They're for people who are sensitive to these chemical products.

What are antiviral facial tissues?
These have antiviral agents that can kill most cold and flu viruses. These only kill the viruses blown into the paper handkerchiefs. Therefore, they prevent the spread of these viruses rather than treat users' symptoms.